Structural analysis of protein-DNA binding specificity and its application to protein-DNA docking assessment

RIC de la Fuente - 2016 - search.proquest.com
DNA-binding proteins are involved in essential biological processes including gene
expression, DNA packaging and DNA repair. They bind to DNA target sequences with …

Statistical analysis of structural determinants for protein–DNA‐binding specificity

RI Corona, J Guo - Proteins: Structure, Function, and …, 2016 - Wiley Online Library
ABSTRACT DNA‐binding proteins play critical roles in biological processes including gene
expression, DNA packaging and DNA repair. They bind to DNA target sequences with …

Novel approach for selecting the best predictor for identifying the binding sites in DNA binding proteins

R Nagarajan, S Ahmad… - Nucleic acids …, 2013 - academic.oup.com
Protein–DNA complexes play vital roles in many cellular processes by the interactions of
amino acids with DNA. Several computational methods have been developed for predicting …

DNA-binding residues and binding mode prediction with binding-mechanism concerned models

YF Huang, CC Huang, YC Liu, YJ Oyang, CK Huang - Bmc Genomics, 2009 - Springer
Background Protein-DNA interactions are essential for fundamental biological activities
including DNA transcription, replication, packaging, repair and rearrangement. Proteins …

Computational approaches for predicting the binding sites and understanding the recognition mechanism of protein–DNA complexes

MM Gromiha, R Nagarajan - Advances in protein chemistry and structural …, 2013 - Elsevier
Protein–DNA recognition plays an important role in the regulation of gene expression.
Understanding the influence of specific residues for protein–DNA interactions and the …

A knowledge-based orientation potential for transcription factor-DNA docking

T Takeda, RI Corona, J Guo - Bioinformatics, 2013 - academic.oup.com
Motivation: Computational modeling of protein–DNA complexes remains a challenging
problem in structural bioinformatics. One of the key factors for a successful protein–DNA …

Predicting protein–DNA interactions by full search computational docking

VA Roberts, ME Pique, LF Ten Eyck… - … : Structure, Function, and …, 2013 - Wiley Online Library
Protein–DNA interactions are essential for many biological processes. X‐ray crystallography
can provide high‐resolution structures, but protein‐DNA complexes are difficult to crystallize …

Discovering the Molecular Basis of DNA-Protein Interaction Specificity

S NAIR - 2022 - dr.iiserpune.ac.in
Specific interactions between DNA and proteins mediate many crucial processes in
biological systems. The basis for this specificity is only known for certain protein families …

PDA-Pred: Predicting the binding affinity of protein-DNA complexes using machine learning techniques and structural features

K Harini, D Kihara, MM Gromiha - Methods, 2023 - Elsevier
Protein–DNA interactions play an important role in various biological processes such as
gene expression, replication, and transcription. Understanding the important features that …

An overview of the prediction of protein DNA-binding sites

J Si, R Zhao, R Wu - International journal of molecular sciences, 2015 - mdpi.com
Interactions between proteins and DNA play an important role in many essential biological
processes such as DNA replication, transcription, splicing, and repair. The identification of …