An Engineered 3D Co-Culture Model of Macrophages and Pancreatic Cancer Organoids to Explore Cellular Interactions in the Tumour Microenvironment
ILY Co - tspace.library.utoronto.ca
Pancreatic ductal adenocarcinoma (PDAC) is the most common form of pancreatic cancer
and is currently the third leading cause of cancer-related deaths in Canada. Despite …
and is currently the third leading cause of cancer-related deaths in Canada. Despite …
An Engineered 3D Co-culture Model of Primary Macrophages and Patient-Derived Tumour Cells to Explore Cellular Responses in the Graded Hypoxic …
IL Co, C Yu, S Lamorte, MT Ciudad, N Landon-Brace… - bioRxiv, 2023 - biorxiv.org
In pancreatic ductal adenocarcinoma (PDAC), tumour associated macrophages (TAMs) are
a heterogeneous immune cell population that interact with cancer cells to promote …
a heterogeneous immune cell population that interact with cancer cells to promote …
Investigating the Effect of Microenvironmental Gradients on Tumour Cell Heterogeneity Using a 3D In Vitro Model of Pancreatic Cancer
NC Landon-Brace - 2023 - search.proquest.com
Pancreatic ductal adenocarcinoma (PDAC) is a high-mortality cancer with no effective
treatment options for the majority of patients. Notably, tumour cell behaviour and response to …
treatment options for the majority of patients. Notably, tumour cell behaviour and response to …
Development of a multicellular pancreatic tumor microenvironment system using patient-derived tumor cells
D Gioeli, CJ Snow, MB Simmers, SA Hoang, RA Figler… - Lab on a Chip, 2019 - pubs.rsc.org
The development of drugs to treat cancer is hampered by the inefficiency of translating pre-
clinical in vitro monoculture and mouse studies into clinical benefit. There is a critical need to …
clinical in vitro monoculture and mouse studies into clinical benefit. There is a critical need to …
Recapitulating the tumor microenvironment in a dish, one cell type at a time
BN Ostendorf - Cell Reports Methods, 2024 - cell.com
The tumor microenvironment harbors a variety of different cell types that differentially impact
tumor biology. In this issue of Cell Reports Methods, Raffo-Romero et al. standardized and …
tumor biology. In this issue of Cell Reports Methods, Raffo-Romero et al. standardized and …
An Engineered Paper-Based 3D Co-Culture Model of Pancreatic Cancer as a Platform for Systems Tissue Engineering
JLC Cardenas - 2023 - search.proquest.com
Pancreatic ductal adenocarcinoma (PDAC) is a deadly form of pancreatic cancer and is
projected to be the third leading cause of cancer-related deaths in Canada this year. With a …
projected to be the third leading cause of cancer-related deaths in Canada this year. With a …
An Engineered Paper-Based 3D Co-Culture Model of Pancreatic Cancer as a Platform for Systems Tissue Engineering
JL Cadavid Cardenas - 2023 - tspace.library.utoronto.ca
Pancreatic ductal adenocarcinoma (PDAC) is a deadly form of pancreatic cancer and is
projected to be the third leading cause of cancer-related deaths in Canada this year. With a …
projected to be the third leading cause of cancer-related deaths in Canada this year. With a …
In vitro model of inflammatory, hypoxia, and cancer stem cell signaling in pancreatic cancer using heterocellular 3-dimensional spheroids
Introduction As one of the most aggressive cancers worldwide, pancreatic cancer is
associated with an extremely poor prognosis. The pancreatic tumor microenvironment …
associated with an extremely poor prognosis. The pancreatic tumor microenvironment …
Abstract B045: Sensitizing the PDAC tumor microenvironment to immune checkpoint therapies: characterization of a PDAC 3D model to decipher immune infiltration
T Bessede, C Freixinos, J Barrat, V Garambois… - Cancer …, 2024 - aacrjournals.org
Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal solid tumor with an unfavorable
prognosis, often resistant to conventional treatments due to its dense stroma rich in Cancer …
prognosis, often resistant to conventional treatments due to its dense stroma rich in Cancer …
A bioengineered heterotypic stroma–cancer microenvironment model to study pancreatic ductal adenocarcinoma
CR Drifka, KW Eliceiri, SM Weber, WJ Kao - Lab on a Chip, 2013 - pubs.rsc.org
Interactions between neoplastic epithelial cells and components of a reactive stroma in
pancreatic ductal adenocarcinoma (PDAC) are of key significance behind the disease's …
pancreatic ductal adenocarcinoma (PDAC) are of key significance behind the disease's …