The Black Box of Cellular and Molecular Events of Plasmodium vivax Merozoite Invasion into Reticulocytes

J Molina-Franky, C Reyes, YA Picón Jaimes… - International Journal of …, 2022 - mdpi.com
Plasmodium vivax is the most widely distributed malaria parasite affecting humans
worldwide, causing~ 5 million cases yearly. Despite the disease's extensive burden, there …

Insights into the invasion biology of Plasmodium vivax

SK Prajapati, OP Singh - Frontiers in Cellular and Infection …, 2013 - frontiersin.org
Plasmodium vivax is the most widely distributed human malaria parasite outside sub Sahara
regions of Africa causing huge morbidity and occasionally being severe and fatal (Kochar et …

The unhealthy attraction of Plasmodium vivax to reticulocytes expressing transferrin receptor 1 (CD71)

B Malleret, L Rénia, B Russell - International journal for parasitology, 2017 - Elsevier
The majority of malaria parasite species prefer to invade reticulocytes, the most infamous
being Plasmodium vivax. While the absence of an in vitro continuous culture method has …

Molecular and cellular interactions defining the tropism of Plasmodium vivax for reticulocytes

U Kanjee, GW Rangel, MA Clark… - Current opinion in …, 2018 - Elsevier
Highlights•P. vivax has multiple and novel invasion ligand families (PvDBPs, PvRBPs,
PvTRAgs).•PvDBP binds to DARC.•PvRBP2b binds to the reticulocyte-tropic transferrin …

Alternative Invasion Mechanisms and Host Immune Response to Plasmodium vivax Malaria: Trends and Future Directions

D Kepple, K Pestana, J Tomida, A Abebe, L Golassa… - Microorganisms, 2020 - mdpi.com
Plasmodium vivax malaria is a neglected tropical disease, despite being more
geographically widespread than any other form of malaria. The documentation of P. vivax …

Dissection of the Plasmodium vivax reticulocyte binding-like proteins (PvRBPs)

J Li, ET Han - Biochemical and biophysical research communications, 2012 - Elsevier
Human malaria, which is caused by infection with Plasmodium, is a serious global public
health problem. The erythrocytic stages are responsible for all of the symptoms and …

Plasmodium vivax ligand-receptor interaction: PvAMA-1 domain I contains the minimal regions for specific interaction with CD71+ reticulocytes

G Arévalo-Pinzón, M Bermúdez, D Hernández… - Scientific reports, 2017 - nature.com
The malarial parasite's invasion is complex, active and coordinated, involving many low and
high affinity interactions with receptors on target cell membrane. Proteomics analysis has …

The cellular and molecular basis for malaria parasite invasion of the human red blood cell

AF Cowman, D Berry, J Baum - Journal of cell Biology, 2012 - rupress.org
Malaria is a major disease of humans caused by protozoan parasites from the genus
Plasmodium. It has a complex life cycle; however, asexual parasite infection within the blood …

Parasite ligand–host receptor interactions during invasion of erythrocytes by Plasmodium merozoites

D Gaur, DCG Mayer, LH Miller - International journal for parasitology, 2004 - Elsevier
Malaria parasites must recognise and invade different cells during their life cycle. The
efficiency with which Plasmodium falciparum invades erythrocytes of all ages is an important …

Characterising PvRBSA: an exclusive protein from Plasmodium species infecting reticulocytes

DA Moreno-Pérez, LA Baquero, DM Chitiva-Ardila… - Parasites & …, 2017 - Springer
Background Plasmodium vivax uses multiple ligand-receptor interactions for preferential
invasion of human reticulocytes. Several of these ligands have been identified by in silico …