Costs and benefits of natural transformation in Acinetobacter baylyi

N Hülter, V Sørum, K Borch-Pedersen, MM Liljegren… - BMC microbiology, 2017 - Springer
Background Natural transformation enables acquisition of adaptive traits and drives genome
evolution in prokaryotes. Yet, the selective forces responsible for the evolution and …

Growth phase-specific evolutionary benefits of natural transformation in Acinetobacter baylyi

ALG Utnes, V Sørum, N Hülter, R Primicerio… - The ISME …, 2015 - academic.oup.com
Natural transformation in bacteria facilitates the uptake and genomic integration of
exogenous DNA. This allows horizontal exchange of adaptive traits not easily achieved by …

Rapid Evolution of Diminished Transformability in Acinetobacter baylyi

JM Bacher, D Metzgar… - Journal of bacteriology, 2006 - Am Soc Microbiol
The reason for genetic exchange remains a crucial question in evolutionary biology.
Acinetobacter baylyi strain ADP1 is a highly competent and recombinogenic bacterium. We …

The RecBCD and SbcCD DNases suppress homology-facilitated illegitimate recombination during natural transformation of Acinetobacter baylyi

K Harms, W Wackernagel - Microbiology, 2008 - microbiologyresearch.org
During natural transformation of Acinetobacter baylyi, the genomic integration of foreign
(non-homologous) DNA is possible when the DNA contains a single segment homologous …

Natural transformation as a tool in Acinetobacter baylyi: streamlined engineering and mutational analysis

SR Bedore, EL Neidle, I Pardo, J Luo, AC Baugh… - Methods in …, 2023 - Elsevier
Natural transformation and homologous recombination in a soil bacterium, Acinetobacter
baylyi ADP1, occur with exceptionally high efficiency. These genetic features can be …

Testing for the fitness benefits of natural transformation during community-embedded evolution

M Winter, K Harms, PJ Johnsen, A Buckling… - …, 2023 - microbiologyresearch.org
Natural transformation is a process where bacteria actively take up DNA from the
environment and recombine it into their genome or reconvert it into extra-chromosomal …

Sexual Isolation in Acinetobacter baylyi Is Locus-Specific and Varies 10,000-Fold Over the Genome

JL Ray, K Harms, OG Wikmark, I Starikova… - Genetics, 2009 - academic.oup.com
Naturally transformable bacteria acquire chromosomal DNA from related species at lower
frequencies than from cognate DNA sources. To determine how genome location affects …

Natural transformation as a tool in Acinetobacter baylyi: Evolution by amplification of gene copy number

I Pardo, SR Bedore, MP Tumen-Velasquez… - Methods in …, 2023 - Elsevier
For many years, the natural competency of Acinetobacter baylyi ADP1 facilitated studies of
bacterial metabolism, biochemistry, and physiology. With the advent of synthetic biology …

Silently transformable: the many ways bacteria conceal their built-in capacity of genetic exchange

L Attaiech, X Charpentier - Current Genetics, 2017 - Springer
Bacteria can undergo genetic transformation by actively integrating genetic information from
phylogenetically related or unrelated organisms. The original function of natural …

Genome instability mediates the loss of key traits by Acinetobacter baylyi ADP1 during laboratory evolution

BA Renda, A Dasgupta, D Leon… - Journal of bacteriology, 2015 - Am Soc Microbiol
Acinetobacter baylyi ADP1 has the potential to be a versatile bacterial host for synthetic
biology because it is naturally transformable. To examine the genetic reliability of this …