Obesity is a metabolic disorder developed by overnutrition and a major cause for insulin
resistance and cardiovascular events. Since adipose tissue is one of the major sites for the …

Background The physiological challenges posed by hypobaric hypoxia warrant exploration
of pharmacological entities to improve acclimatization to hypoxia. The present study …

Mechanical ventilation (MV) performed in respiratory failure patients to maintain lung
function leads to ventilator-induced lung injury (VILI). This study investigates the role of …

Autism spectrum disorders (ASD) are a heterogeneous group of neurodevelopmental
disorders generally characterized by repetitive behaviors and difficulties in communication …

Metabolic pathways are complex and intertwined. Deficiencies in one or more enzymes in a
given pathway are directly linked with genetic diseases, most of them having devastating …

Brain is a vital organ of the human body which performs very important functions such as
analysis, processing, coordination, and execution of electrical signals. For this purpose, it …

Deoxysphingolipids (1-deoxySLs) are structurally distinguished from canonical
sphingolipids (SLs) by absenting the essential C1-OH group that can be found in the daily …

Sphingolipids are structurally diverse and their metabolic pathways highly complex, which
makes it difficult to follow all of the subspecies in a biological system, even using" lipidomic" …

Many investigations suggest the pivotal role of sphingolipids in the pathogenesis of lifestyle
diseases such as myocardial infarction, hypertension, stroke, diabetes mellitus type 2 and …

Docosahexaenoic (DHA) and arachidonic acids (AA) are polyunsaturated fatty acids
(PUFAs), major components of brain tissue and neural systems, and the precursors of a …