Background Reactive oxygen species are important mediators exerting toxic effects on
various organs during ischemia-reperfusion (IR) injury. We hypothesized that adipose …

Background: Renal ischemia followed by reperfusion leads to acute renal failure in both
native kidneys and renal allograft. This study aimed at investigating the effects …

Background In this study, we tested the hypothesis that a combined adipose-derived
mesenchymal stem cell (ADMSC) and ADMSC-derived exosome therapy protected rat …

Background Acute kidney injury (AKI) is a critical condition for kidney and other remote
organs, including the lung. However, available treatments for AKI are limited. In this study …

Abstract Background Mesenchymal stem cells (MSCs) have been reported to promote the
regeneration of injured tissue via their paracrine abilities, which are enhanced by hypoxic …

Diabetic nephropathy is the leading cause of end-stage renal disease. The aim of this study
was to investigate the renoprotective effects of autologous transplantation of adipose …

Background Acute kidney injury (AKI) is an emerging global healthcare issue without
effective therapy yet. Autophagy recycles damaged organelles and helps maintain tissue …

Hypoxia preconditioning has been confirmed as an effective strategy to enhance the
therapeutic potentials of mesenchymal stem cells (MSCs), such as for myocardial ischemia …

The recent findings indicate that under conditions of severe tubular injuries, transplantation
of mesenchymal stem cells (MSCs) may be a promising treatment in acute kidney diseases; …

Background/Aims: The therapeutic potential of extracellular vesicles (EVs) derived from
mesenchymal stromal cells (MSCs) in kidney injury has been largely reported. However …