Binge drinking is a major public health issue and ethanol-related liver insult may play a
major role in the pathology of alcoholic liver disease. However, the degree of oxidative …

Alcohol binge drinking, especially in teenagers and young adults is a major public health
issue in the UK, with the number of alcohol related liver disorders steadily increasing …

Acetaldehyde (Ac), the main metabolite of ethanol oxidation, is a very reactive compound
involved in alcohol-induced liver damage. In the present work, we studied the effect of Ac in …

BACKGROUND & AIMS: The precise pathogenic significance of oxidative injury in the
evolution of alcohol-induced liver disease is still obscure. The present report was designed …

Alcohol consumption is implicated in the genesis of a spectrum of liver abnormalities, which
are associated with a number of factors. In the present study, time-dependent effects of …

Alcohol consumption is one of the leading causes of the global burden of disease and
results in high healthcare and economic costs. Heavy alcohol misuse leads to alcohol …

The biotransformation of ethanol in hepatocytes leads to the production of acetaldehyde, an
organic compound even more toxic than ethanol and responsible of practically all noxious …

Binge drinking, a common pattern of alcohol ingestion, is known to potentiate liver injury
caused by chronic alcohol abuse. This study was aimed at investigating the effects of acute …

Alcoholic liver disease (ALD) has caused a serious burden on public and personal health in
crowd with ethanol abuse. The effects of insulin resistance (IR) on ALD and the mechanisms …

In this 9-topic review series, we will provide an insight into the pathogenesis of alcohol-
mediated liver damage. The aspects addressed in the reviews cover the most important …