Roles of Porphyromonas gingivalis and its virulence factors in periodontitis

W Xu, W Zhou, H Wang, S Liang - Advances in protein chemistry and …, 2020 - Elsevier
Periodontitis is an infection-driven inflammatory disease, which is characterized by gingival
inflammation and bone loss. Periodontitis is associated with various systemic diseases …

Porphyromonas gingivalis-Epithelial Cell Interactions in Periodontitis

E Andrian, D Grenier… - Journal of dental …, 2006 - journals.sagepub.com
Emerging data on the consequences of the interactions between invasive oral bacteria and
host cells have provided new insights into the pathogenesis of periodontal disease. Indeed …

Molecular strategies underlying Porphyromonas gingivalis virulence

IL Silva, E Cascales - Journal of Molecular Biology, 2021 - Elsevier
The anaerobic Gram-negative bacterium Porphyromonas gingivalis is considered the
keystone of periodontitis diseases, a set of inflammatory conditions that affects the tissues …

Porphyromonas gingivalis: An Overview of Periodontopathic Pathogen below the Gum Line

KY How, KP Song, KG Chan - Frontiers in microbiology, 2016 - frontiersin.org
Periodontal disease represents a group of oral inflammatory infections initiated by oral
pathogens which exist as a complex biofilms on the tooth surface and cause destruction to …

Porphyromonas gingivalis virulence factors involved in subversion of leukocytes and microbial dysbiosis

C Zenobia, G Hajishengallis - Virulence, 2015 - Taylor & Francis
The oral bacterium Porphyromonas gingivalis has special nutrient requirements due to its
asaccharolytic nature subsisting on small peptides cleaved from host proteins. Using …

Porphyromonas gingivalis Virulence Factors and Clinical Significance in Periodontal Disease and Coronary Artery Diseases

LH Aleksijević, M Aleksijević, I Škrlec, M Šram, M Šram… - Pathogens, 2022 - mdpi.com
Porphyromonas gingivalis is a gram-negative, anaerobic bacterium that lives in the oral
cavity. It is an integral part of the oral microbiome, which includes more than 500 types of …

Porphyromonas gingivalis: Major Periodontopathic Pathogen Overview

J Mysak, S Podzimek, P Sommerova… - Journal of …, 2014 - Wiley Online Library
Porphyromonas gingivalis is a Gram‐negative oral anaerobe that is involved in the
pathogenesis of periodontitis and is a member of more than 500 bacterial species that live in …

Molecular Interaction of Porphyromonas gingivalis with Host Cells: Implication for the Microbial Pathogenesis of Periodontal Disease

A Amano - Journal of periodontology, 2003 - Wiley Online Library
Porphyromonas gingivalis is a predominant periodontal pathogen, which expresses a
number of potential virulence factors involved in the pathogenesis of periodontitis. Among …

Porphyromonas gingivalis, a Long-Range Pathogen: Systemic Impact and Therapeutic Implications

H Mulhall, O Huck, S Amar - Microorganisms, 2020 - mdpi.com
Periodontitis is an inflammatory disease associated with a dysbiosis of the oral flora
characterized by a chronic sustained inflammation leading to destruction of tooth-supporting …

Porphyromonas gingivalis adopts intricate and unique molecular mechanisms to survive and persist within the host: a critical update

A Chopra, SG Bhat, K Sivaraman - Journal of Oral Microbiology, 2020 - Taylor & Francis
ABSTRACT Porphyromonas. gingivalis (P. gingivalis) is an obligate, asaccharolytic, gram-
negative bacteria commonly associated with increased periodontal and systemic …