STUDY QUESTION Is there an association between the need for medical puberty induction
and the diagnosis or treatment received in girls who have undergone cryopreservation of …

Research question Is ovarian tissue cryopreservation (OTC) for fertility preservation in
prepubertal and adolescent girls safe, and who would benefit most from the procedure …

With the increasing numbers of survivors of cancer in young people, future fertility and
ovarian function are important considerations that should be discussed before treatment …

With steadily improving survival rates for childhood cancer and other pediatric medical
conditions, it has become increasingly important to minimize anticipated adverse effects of …

Introduction The preservation of fertility is an integral part of care of children requiring
gonadotoxic treatments for cancer or non‐malignant diseases. In France, the …

Ovarian tissue cryopreservation is an option to preserve reproductive potential in patients
who must urgently undergo aggressive chemotherapy and/or radiotherapy or who have …

Background Loss of fertility is one of the long‐term adverse effects of high‐dose
chemotherapy or total body irradiation for cancer, even in children. Ovarian tissue …

Cancer during childhood and adolescence remains a major public health issue, affecting a
significant portion of this age group. Although newer anti-cancer treatments have improved …

Children that undergo treatment for cancer are at risk of suffering from subfertility or
hormonal dysfunction due to the detrimental effects of radiotherapy and chemotherapeutic …

STUDY QUESTION Do the benefits of ovarian tissue cryopreservation outweigh the risks for
patients seeking to preserve fertility before gonadotoxic treatment in various indications …