Pathobiological mechanisms of peritoneal adhesions: The mesenchymal transition of rat peritoneal mesothelial cells induced by TGF-β1 and IL-6 requires activation of …
X Jin, S Ren, E Macarak, J Rosenbloom - Matrix Biology, 2016 - Elsevier
Peritoneal adhesions, primarily caused by surgical procedures, are the leading cause of
pelvic pain, bowel obstruction, and infertility. TGF-β1 and IL-6 have been found to be …
pelvic pain, bowel obstruction, and infertility. TGF-β1 and IL-6 have been found to be …
[HTML][HTML] TGF-β1 promotes transition of mesothelial cells into fibroblast phenotype in response to peritoneal injury in a cell culture model
P Falk, E Angenete, M Bergström… - International Journal of …, 2013 - Elsevier
Background Peritoneal adhesions are a clinical problem. A key to the understanding of
peritoneal adhesions is to study the healing of mesothelial cells within the peritoneal cavity …
peritoneal adhesions is to study the healing of mesothelial cells within the peritoneal cavity …
Mesothelial‐to‐mesenchymal transition in the pathogenesis of post‐surgical peritoneal adhesions
P Sandoval, JA Jiménez‐Heffernan… - The Journal of …, 2016 - Wiley Online Library
Peritoneal adhesions (PAs) are fibrotic bands formed between bowel loops, solid organs,
and the parietal peritoneum, which may appear following surgery, infection or …
and the parietal peritoneum, which may appear following surgery, infection or …
Platelet derived growth factor B and epithelial mesenchymal transition of peritoneal mesothelial cells
Platelet derived growth factor (PDGF) is involved in wound healing in various organ
systems. Its potential role in the context of peritoneal injury following long-term peritoneal …
systems. Its potential role in the context of peritoneal injury following long-term peritoneal …
[HTML][HTML] Macrophages induce the adhesion phenotype in normal peritoneal fibroblasts
JC White, ZL Jiang, MP Diamond, GM Saed - Fertility and sterility, 2011 - Elsevier
OBJECTIVE: To determine whether macrophages, exposed to hypoxia, stimulate primary
cultures of fibroblasts to acquire the adhesion phenotype. The adhesion phenotype has …
cultures of fibroblasts to acquire the adhesion phenotype. The adhesion phenotype has …
TGF-β system: the principal profibrotic mediator of peritoneal adhesion formation
N Chegini - Seminars in reproductive medicine, 2008 - thieme-connect.com
Whether induced by infection, inflammation, ischemia, and/or surgical injury, peritoneal
adhesions are the leading cause of pelvic pain, bowel obstruction, and infertility. Although …
adhesions are the leading cause of pelvic pain, bowel obstruction, and infertility. Although …
[HTML][HTML] Mechanisms of peritoneal mesothelial cells in peritoneal adhesion
R Wang, T Guo, J Li - Biomolecules, 2022 - mdpi.com
A peritoneal adhesion (PA) is a fibrotic tissue connecting the abdominal or visceral organs to
the peritoneum. The formation of PAs can induce a variety of clinical diseases. However …
the peritoneum. The formation of PAs can induce a variety of clinical diseases. However …
[HTML][HTML] Hypoxia, cytokines and stromal recruitment: parallels between pathophysiology of encapsulating peritoneal sclerosis, endometriosis and peritoneal …
RB Wilson - Pleura and peritoneum, 2018 - degruyter.com
Peritoneal response to various kinds of injury involves loss of peritoneal mesothelial cells
(PMC), danger signalling, epithelial-mesenchymal transition and mesothelial-mesenchymal …
(PMC), danger signalling, epithelial-mesenchymal transition and mesothelial-mesenchymal …
Expression of matrix metalloproteinases and tissue inhibitor of matrix metalloproteinases in mesothelial cells and their regulation by transforming growth factor‐β1
C Ma, RW Tarnuzzer, N Chegini - Wound repair and …, 1999 - Wiley Online Library
Tissue injury and pelvic inflammation often results in peritoneal scar tissue formation. The
objective of this study was to determine whether mesothelial cells which line the peritoneal …
objective of this study was to determine whether mesothelial cells which line the peritoneal …
Disruption of the integrity of human peritoneal mesothelium by interleukin-1β and tumor necrosis factor-α
S Stadlmann, R Raffeiner, A Amberger, R Margreiter… - Virchows Archiv, 2003 - Springer
Inflammatory and neoplastic disease processes of the abdominal cavity are frequently
associated with disruption of the integrity of the peritoneal mesothelium. In the present study …
associated with disruption of the integrity of the peritoneal mesothelium. In the present study …