Site-specific lysine acetylation stoichiometry across subcellular compartments
AJ Lindahl, AJ Lawton, J Baeza, JA Dowell… - … : Methods and Protocols, 2019 - Springer
Posttranslational modifications of proteins control many complex biological processes,
including genome expression, chromatin dynamics, metabolism, and cell division through a …
including genome expression, chromatin dynamics, metabolism, and cell division through a …
Revealing dynamic protein acetylation across subcellular compartments
Protein acetylation is a widespread post-translational modification implicated in many
cellular processes. Recent advances in mass spectrometry have enabled the cataloging of …
cellular processes. Recent advances in mass spectrometry have enabled the cataloging of …
[图书][B] High-resolution mass spectrometry to identify and quantify acetylation protein targets
The dynamic nature of protein posttranslational modification (PTM) allows cells to rapidly
respond to changes in their environment, such as nutrition, stress, or signaling. Lysine …
respond to changes in their environment, such as nutrition, stress, or signaling. Lysine …
Site-specific identification of lysine acetylation stoichiometries in mammalian cells
Functional characterization of the lysine acetylation pathway requires quantitative
measurement of the modification abundance at the stoichiometry level. Here, we developed …
measurement of the modification abundance at the stoichiometry level. Here, we developed …
Targeted large‐scale analysis of protein acetylation
N Mischerikow, AJR Heck - Proteomics, 2011 - Wiley Online Library
Protein modifications are biologically important events that may be studied by mass
spectrometry‐based high‐throughput proteome analyses. In recent years, several new …
spectrometry‐based high‐throughput proteome analyses. In recent years, several new …
[PDF][PDF] Quantifying dynamic protein acetylation using quantitative stoichiometry
Abstract: Protein acetylation is a widespread post-translational modification that is
implicated in many cellular processes. Emergent technologies such as mass spectrometry …
implicated in many cellular processes. Emergent technologies such as mass spectrometry …
A method to determine lysine acetylation stoichiometries
ES Nakayasu, S Wu, MA Sydor… - … journal of proteomics, 2014 - Wiley Online Library
Lysine acetylation is a common protein posttranslational modification that regulates a variety
of biological processes. A major bottleneck to fully understanding the functional aspects of …
of biological processes. A major bottleneck to fully understanding the functional aspects of …
Validation of protein acetylation by mass spectrometry
Due to the key role of posttranslational modifications (PTMs) such as lysine acetylation in
numerous signaling and regulatory pathways, the ability to identify novel PTMs and to …
numerous signaling and regulatory pathways, the ability to identify novel PTMs and to …
Isotopic labeling and quantitative proteomics of acetylation on histones and beyond
Lysine acetylation is an important posttranslational modification (PTM) that regulates the
function of proteins by affecting their localization, stability, binding, and enzymatic activity …
function of proteins by affecting their localization, stability, binding, and enzymatic activity …
Site-specific determination of lysine acetylation stoichiometries on the proteome-scale
Posttranslational modification of proteins (PTMs) offers a versatile mechanism to fine-tune
the structure, activity, and interactions of the target proteins. Understanding the dynamics …
the structure, activity, and interactions of the target proteins. Understanding the dynamics …