HIV persistence on antiretroviral therapy and barriers to a cure
JM Sung, DM Margolis - HIV Vaccines and Cure: The Path Towards …, 2018 - Springer
HIV persists within the body despite successful suppression of virus replication with
antiretroviral therapy (ART). HIV lurks in latent and active reservoirs, leading to rebound of …
antiretroviral therapy (ART). HIV lurks in latent and active reservoirs, leading to rebound of …
[HTML][HTML] HIV reservoirs as obstacles and opportunities for an HIV cure
The persistence of HIV reservoirs remains a formidable obstacle to achieving sustained
virologic remission in HIV-infected individuals after antiretroviral therapy (ART) is …
virologic remission in HIV-infected individuals after antiretroviral therapy (ART) is …
[HTML][HTML] HIV persistence in the setting of antiretroviral therapy: when, where and how does HIV hide?
DA Kulpa, N Chomont - Journal of virus eradication, 2015 - Elsevier
Advances in the treatment of HIV infection have dramatically reduced the death rate from
AIDS and improved the quality of life of many HIV-infected individuals. However, the …
AIDS and improved the quality of life of many HIV-infected individuals. However, the …
[HTML][HTML] Targeting the latent reservoir for HIV-1
S Sengupta, RF Siliciano - Immunity, 2018 - cell.com
Antiretroviral therapy can effectively block HIV-1 replication and prevent or reverse
immunodeficiency in HIV-1-infected individuals. However, viral replication resumes within …
immunodeficiency in HIV-1-infected individuals. However, viral replication resumes within …
Developing strategies for HIV-1 eradication
CM Durand, JN Blankson, RF Siliciano - Trends in immunology, 2012 - cell.com
Highly active antiretroviral therapy (HAART) suppresses HIV-1 replication, transforming the
outlook for infected patients. However, reservoirs of replication-competent forms of the virus …
outlook for infected patients. However, reservoirs of replication-competent forms of the virus …
Can HIV be cured? Mechanisms of HIV persistence and strategies to combat it
DH Hamer - Current HIV research, 2004 - ingentaconnect.com
Stable remission is the ultimate goal of HIV therapy. A review of recent studies on the ability
of HIV to persist despite highly active antiretroviral therapy (HAART) and immune stimulation …
of HIV to persist despite highly active antiretroviral therapy (HAART) and immune stimulation …
Reservoirs for HIV-1
RF Siliciano - Current Infectious Disease Reports, 1999 - Springer
The success of antiretroviral therapy for HIV-1 infection has generated interest in
mechanisms by which the virus can persist in the body despite the presence of drugs that …
mechanisms by which the virus can persist in the body despite the presence of drugs that …
HIV persistence and the prospect of long-term drug-free remissions for HIV-infected individuals
HIV infection can persist in spite of efficacious antiretroviral therapies. Although incomplete
inhibition of viral replication may contribute to this phenomenon, this is largely due to the …
inhibition of viral replication may contribute to this phenomenon, this is largely due to the …
HIV-1 reservoir persistence and decay: Implications for cure strategies
EF Kreider, KJ Bar - Current HIV/AIDS Reports, 2022 - Springer
Abstract Purpose of Review Despite suppressive antiretroviral therapy (ART), a viral
reservoir persists in individuals living with HIV that can reignite systemic replication should …
reservoir persists in individuals living with HIV that can reignite systemic replication should …
Reservoirs for HIV-1: mechanisms for viral persistence in the presence of antiviral immune responses and antiretroviral therapy
T Pierson, J McArthur… - Annual review of …, 2000 - annualreviews.org
The success of combination antiretroviral therapy for HIV-1 infection has generated interest
in mechanisms by which the virus can persist in the body despite the presence of drugs that …
in mechanisms by which the virus can persist in the body despite the presence of drugs that …