[HTML][HTML] Dissecting the mechanism of action of intravenous immunoglobulin in human autoimmune disease: lessons from therapeutic modalities targeting Fcγ …

A Shock, D Humphreys, F Nimmerjahn - Journal of Allergy and Clinical …, 2020 - Elsevier
Since the first description of the administration of high doses of pooled serum IgG, also
referred to as intravenous IgG (IVIg) therapy, as being able to ameliorate various …

Intravenous immunoglobulin: Mechanism of action in autoimmune and inflammatory conditions

J Bayry, EA Ahmed, D Toscano-Rivero… - The Journal of Allergy …, 2023 - Elsevier
Intravenous immunoglobulin (IVIG) is the mainstay of therapy for humoral immune
deficiencies and numerous inflammatory disorders. Although the use of IVIG may be …

Intravenous immunoglobulins in autoimmune and inflammatory diseases: a mechanistic perspective

S Siberil, S Elluru, S GRAFF‐DUBOIS… - Annals of the New …, 2007 - Wiley Online Library
Initially used for the treatment of immunodeficiencies, intravenous immunoglobulins (IVIg)
have increasingly been used as immunomodulatory agents in autoimmune and …

Modulation of the cellular immune system by intravenous immunoglobulin

T Tha-In, J Bayry, HJ Metselaar, SV Kaveri… - Trends in …, 2008 - cell.com
Intravenous immunoglobulin (IVIg) is therapeutically used in a variety of immune-mediated
diseases. The beneficial effects of IVIg in auto-antibody-mediated diseases can be …

[HTML][HTML] Differences in anti-inflammatory actions of intravenous immunoglobulin between mice and men: more than meets the eye

ASW Tjon, R van Gent, TB Geijtenbeek… - Frontiers in …, 2015 - frontiersin.org
Intravenous immunoglobulin (IVIg) is a therapeutic preparation of polyspecific human IgGs
purified from plasma pooled from thousands of individuals. When administered at a high …

Intravenous immunoglobulin therapy for autoimmune diseases

Y Arnson, Y Shoenfeld, H Amital - Autoimmunity, 2009 - Taylor & Francis
Therapeutic approaches for autoimmune diseases are primarily based on suppressive
measures that down regulate an over productive immune system. The increasing availability …

IVIG-mediated effector functions in autoimmune and inflammatory diseases

C Galeotti, SV Kaveri, J Bayry - International immunology, 2017 - academic.oup.com
Intravenous immunoglobulin (IVIG) is a pooled preparation of normal IgG obtained from
several thousand healthy donors. It is widely used in the immunotherapy of a large number …

Intravenous immunoglobulin therapy: how does IgG modulate the immune system?

I Schwab, F Nimmerjahn - Nature Reviews Immunology, 2013 - nature.com
Intravenous immunoglobulin (IVIG) preparations comprise pooled IgG antibodies from the
serum of thousands of donors and were initially used as an IgG replacement therapy in …

[HTML][HTML] Immunomodulation by IVIg and the role of Fc-gamma receptors: classic mechanisms of action after all?

SQ Nagelkerke, TW Kuijpers - Frontiers in immunology, 2015 - frontiersin.org
Intravenous IgG (IVIg) contains polyclonal immunoglobulin G (IgG) from thousands of
donors. It is administered at a low dose at regular intervals as antibody replacement therapy …

Facing the enigma of immunomodulatory effects of intravenous immunoglobulin

T Sapir, Y Shoenfeld - Clinical reviews in allergy & immunology, 2005 - Springer
Intravenous immunoglobulin (IVIg) is a safe remedy for a number of conditions; it is
produced from human plasma of thousands of healthy donors. The therapeutic effect of IVIg …