DNA repair and systemic lupus erythematosus

R Meas, MJ Burak, JB Sweasy - DNA repair, 2017 - Elsevier
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with no known cure
that affects at least five million people worldwide. Monozygotic twin concordance and …

[HTML][HTML] DNA damage and deficiencies in the mechanisms of its repair: implications in the pathogenesis of systemic lupus erythematosus

MP Mireles-Canales, SA González-Chávez… - Journal of Immunology …, 2018 - hindawi.com
Systemic lupus erythematosus (SLE) is a perplexing and potentially severe disease, the
pathogenesis of which is yet to be understood. SLE is considered to be a multifactorial …

The genetic contribution to systemic lupus erythematosus.

LA Criswell - Bulletin of the NYU hospital for joint diseases, 2008 - search.ebscohost.com
We are currently witnessing an explosion of information about the genetic contribution to
complex human diseases such as systemic lupus erythematosus (SLE). These genetic …

Genetic susceptibility to systemic lupus erythematosus in the genomic era

Y Deng, BP Tsao - Nature Reviews Rheumatology, 2010 - nature.com
Our understanding of the genetic basis of systemic lupus erythematosus (SLE) has been
rapidly advanced using large-scale, case–control, candidate gene studies as well as …

Finding genes for SLE: complex interactions and complex populations

ME Alarcón-Riquelme, L Prokunina - Journal of autoimmunity, 2003 - Elsevier
Many years of work, multiplex family collection and endless genotyping finally give fruit. The
original aim cannot be lost. The aim is not only to identify mutations involved in susceptibility …

Genetics of systemic lupus erythematosus: clinical implications

KE Sullivan - Rheumatic Disease Clinics of North America, 2000 - Elsevier
Systemic lupus erythematosus (SLE) is the prototypic systemic autoimmune disease. The
clinical features are well-known: production of autoantibodies, immune complex–mediated …

Advances in lupus genetics and epigenetics

Y Deng, BP Tsao - Current opinion in rheumatology, 2014 - journals.lww.com
Advances in lupus genetics and epigenetics : Current Opinion in Rheumatology Advances in
lupus genetics and epigenetics : Current Opinion in Rheumatology Log in or Register …

Recent insights into the genetic basis of systemic lupus erythematosus

KL Moser, JA Kelly, CJ Lessard, JB Harley - Genes & Immunity, 2009 - nature.com
Genetic variation was first shown to be important in systemic lupus erythematosus (SLE or
lupus) in the 1970s with associations in the human leukocyte antigen region. Almost four …

Advances in lupus genetics

TB Niewold - Current opinion in rheumatology, 2015 - journals.lww.com
Advances in lupus genetics : Current Opinion in Rheumatology Advances in lupus genetics :
Current Opinion in Rheumatology Log in or Register Subscribe to journalSubscribe Get new …

Loss-of-function variant in DNASE1L3 causes a familial form of systemic lupus erythematosus

SM Al-Mayouf, A Sunker, R Abdwani, SA Abrawi… - Nature …, 2011 - nature.com
Systemic lupus erythematosus (SLE) is a complex autoimmune disease that causes
substantial morbidity. As is typical for many other multifactorial disorders, much of the …