The human airway is protected by an efficient innate defence mechanism that requires 28
healthy secretion of airway surface liquid (ASL) to clear pathogens from the lungs. Most 29 …

The human airway is protected by an efficient innate defense mechanism that requires
healthy secretion of airway surface liquid (ASL) to clear pathogens from the lungs. Most of …

Cystic fibrosis (CF) is caused by mutations in the CF transmembrane conductance regulator
(CFTR) protein, an epithelial chloride channel expressed in the airways, pancreas, testis …

Cystic fibrosis (CF) results from mutations that disrupt CF transmembrane conductance
regulator (CFTR), an anion channel found mainly in apical membranes of epithelial cells. CF …

The airways are lined with a film of liquid about 10 µm deep that is in two layers. Around the
cilia is the watery periciliary sol. Over this is a mucous blanket that traps inhaled particles …

Malfunction of airway submucosal glands contributes to the pathology of cystic fibrosis (CF),
and cell cultures of CF human airway glands show defects in Cl− and water transport …

Cystic fibrosis (CF) lung disease, caused by abnormal ion transport because of deficient
CFTR (cystic fibrosis transmembrane conductance regulator) function, is characterized by a …

Cystic Fibrosis (CF) is an autosomal recessive condition caused by mutations in the gene
encoding the Cystic Fibrosis Transmembrane conductance Regulator (CFTR) anion …

Abnormal airway secretions characterize asthma" and cystic fibrosis (CF), 13.73 obstructive
airway diseases with different clinical courses. Whereas airway secretions that are retained …

Defective transepithelial electrolyte transport is thought to initiate cystic fibrosis (CF) lung
disease. Yet, how loss of CFTR affects electrolyte transport remains uncertain. CFTR−/− pigs …