A high cyclic adenosine monophosphate (cAMP) level in fully-grown immature oocytes
prevents meiotic resumption. In Xenopus, inhibitory cAMP is synthesized within oocytes …

Maintenance of meiotic prophase arrest in fully grown vertebrate oocytes depends on an
elevated level of cAMP in the oocyte. To investigate how the cAMP level is regulated, we …

In mammalian oocytes, the maintenance of meiotic prophase I arrest prior to the surge of LH
that stimulates meiotic maturation depends on a high level of cAMP within the oocyte. In …

Progesterone‐induced oocyte maturation is thought to involve the inhibition of an oocyte
adenylyl cyclase and reduction of intracellular cAMP. Our previous studies demonstrated …

Background: Progesterone induces the resumption of meiosis (maturation) in Xenopus
oocytes through a nongenomic mechanism involving inhibition of an oocyte adenylyl …

Progesterone, produced by follicular cells, induces Xenopus laevis oocyte maturation
through a very early event that inhibits the activity of the adenylyl cyclase effector system …

Mammalian oocytes are maintained at the G2/M border of the first meiotic division (germinal
vesicle, GV) often for years before being ovulated. This event is determined by the status of …

In nearly every vertebrate species, elevated intracellular cAMP maintains oocytes in
prophase I of meiosis. Prior to ovulation, gonadotropins trigger various intra-ovarian …

The stimulatory heterotrimeric G s protein alpha subunit (G s α) is a ubiquitous guanine
nucleotide-binding protein that regulates the intracellular cAMP signaling pathway and …

Throughout folliculogenesis, mammalian oocytes are arrested at the diplotene stage of the
first meiotic prophase, or germinal vesicle (GV) stage. Meiotic competence is defined as the …