Publisher Summary This chapter describes that the poly (A) segment in mRNA provides a
dramatic example of an accessory polynucleotide sequence that is clearly not involved in …

A structure consisting of poly (A) complexed with other components is released from
polysomes by ribonuclease treatment. The poly (A) complex has a sedimentation value of 12 …

Chinese hamster and mouse sarcoma 180 ascites cells, treated with high levels of
actinomycin D, still carry out limited poly (A) synthesis. The residual activity, which consists …

Polyadenylate sequences are found covalently linked to yeast mRNA molecules. The poly
(A) sequences are relatively homogeneous in size and have an average chain length of …

Messenger RNA molecules in eukaryotic cells are modified at both their 5'and 3'ends, by
a'cap'structure at the former and a poly (A)'tail'at the latter. Formation of the 3'ends of most …

Polyadenylate sequences have been found covalently linked in heterogeneous DNA-like
nuclear RNA of HeLa cells. This poly (A) material seems homogeneous in size and accounts …

The occurrence of poly (A) as a component of eukaryotic messenger RNA has been known
for about 10 years, but the role of this sequence is still something of a mystery. The poly (A) …

Jozef Mendecki. l Se Yong Lee, § and George Brawerman* abstract: It has been shown
recently that rapidly labeled polysomal RNA and nuclear RNA molecules contain a large …

Department of Biological Sciences, Columbia University, New York, NY 10027 mRNAs in
eukaryotic cells, as every fresh-man biology student of the last 20 or so years has learned …

The investigation of eukaryotic mRNA has focussed on molecules that possess a 3'-terminal
poly (A) seg ment [l-3] since they can be isolated easily by virtue of their high affinity for oligo …