[HTML][HTML] Omicron escapes the majority of existing SARS-CoV-2 neutralizing antibodies
Abstract The SARS-CoV-2 B. 1.1. 529 (Omicron) variant contains 15 mutations of the
receptor-binding domain (RBD). How Omicron evades RBD-targeted neutralizing antibodies …
receptor-binding domain (RBD). How Omicron evades RBD-targeted neutralizing antibodies …
B. 1.1. 529 escapes the majority of SARS-CoV-2 neutralizing antibodies of diverse epitopes
Y Cao, J Wang, F Jian, T Xiao, W Song, A Yisimayi… - BioRxiv, 2021 - biorxiv.org
Abstract The SARS-CoV-2 B. 1.1. 529 variant (Omicron) contains 15 mutations on the
receptor-binding domain (RBD). How Omicron would evade RBD neutralizing antibodies …
receptor-binding domain (RBD). How Omicron would evade RBD neutralizing antibodies …
[HTML][HTML] Broadly neutralizing antibodies overcome SARS-CoV-2 Omicron antigenic shift
The recently emerged SARS-CoV-2 Omicron variant encodes 37 amino acid substitutions in
the spike protein, 15 of which are in the receptor-binding domain (RBD), thereby raising …
the spike protein, 15 of which are in the receptor-binding domain (RBD), thereby raising …
Structural and functional analysis of a potent sarbecovirus neutralizing antibody
SARS-CoV-2 is a newly emerged coronavirus responsible for the current COVID-19
pandemic that has resulted in more than one million infections and 73,000 deaths,. Vaccine …
pandemic that has resulted in more than one million infections and 73,000 deaths,. Vaccine …
[HTML][HTML] Considerable escape of SARS-CoV-2 Omicron to antibody neutralization
D Planas, N Saunders, P Maes, F Guivel-Benhassine… - Nature, 2022 - nature.com
Abstract The SARS-CoV-2 Omicron variant was first identified in November 2021 in
Botswana and South Africa,–. It has since spread to many countries and is expected to …
Botswana and South Africa,–. It has since spread to many countries and is expected to …
[HTML][HTML] SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies
Abstract The coronavirus disease 2019 (COVID-19) pandemic presents an urgent health
crisis. Human neutralizing antibodies that target the host ACE2 receptor-binding domain …
crisis. Human neutralizing antibodies that target the host ACE2 receptor-binding domain …
[HTML][HTML] SARS-CoV-2 variant Omicron: currently the most complete “escapee” from neutralization by antibodies and vaccines
M Li, F Lou, H Fan - Signal Transduction and Targeted Therapy, 2022 - nature.com
On December 23, 2021, five groups published their research results of clinical-approved
monoclonal antibodies, convalescent serum, and vaccine serum against B. 1.1. 529 …
monoclonal antibodies, convalescent serum, and vaccine serum against B. 1.1. 529 …
Structural basis for potent antibody neutralization of SARS-CoV-2 variants including B. 1.1. 529
The rapid spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) B.
1.1. 529 (Omicron) variant and its resistance to neutralization by vaccinee and convalescent …
1.1. 529 (Omicron) variant and its resistance to neutralization by vaccinee and convalescent …
[HTML][HTML] Potent and protective IGHV3-53/3-66 public antibodies and their shared escape mutant on the spike of SARS-CoV-2
Neutralizing antibodies (nAbs) to SARS-CoV-2 hold powerful potentials for clinical
interventions against COVID-19 disease. However, their common genetic and biologic …
interventions against COVID-19 disease. However, their common genetic and biologic …
[HTML][HTML] Vaccines elicit highly conserved cellular immunity to SARS-CoV-2 Omicron
J Liu, A Chandrashekar, D Sellers, J Barrett… - Nature, 2022 - nature.com
The highly mutated SARS-CoV-2 Omicron (B. 1.1. 529) variant has been shown to evade a
substantial fraction of neutralizing antibody responses elicited by current vaccines that …
substantial fraction of neutralizing antibody responses elicited by current vaccines that …