BACKGROUND: Acute encephalitis and encephalopathy (AEE) are life-threatening
diseases in children. However, no laboratory examinations are performed for their early …

Background Acute encephalitis and encephalopathy are life-threatening diseases in
children. However, no laboratory examinations are performed for their early diagnosis and …

We simultaneously measured 16 cytokines/chemokines in cerebrospinal fluid (CSF) from 14
patients with acute disseminated encephalomyelitis (ADEM) and 20 controls using a …

Background Increased cerebrospinal fluid (CSF) β2-microglobulin (β2-MG) values are
attributed to immune activation, lymphoid cell turnover and release of tissue destruction in …

We measured β2-microglobulin (β2-M), soluble interleukin-2 receptor (sIL-2R), and soluble
CD8 (sCD8) antigen levels in paired cerebrospinal fluid (CSF) and sera from patients with …

In multiple sclerosis, there have been many reports on matrix metalloproteinases (MMPs)
and their tissue inhibitors (TIMPs). However, MMPs and TIMPs have not been reported in …

Background and objective: Acute disseminated encephalomyelitis (ADEM) and relapsing–
remitting multiple sclerosis (RRMS) share overlapping clinical, radiologic and laboratory …

Background Pediatricians sometimes see patients with severe aseptic meningitis and
prolonged fever or severe headache, or both. This condition generally has a good prognosis …

Alpha2-macroglobulin is a protease inhibitor that enhances procoagulant properties via the
neutralization of plasmin, plasminogen activators and metalloproteinases. Additionally …

Acute disseminated encephalomyelitis (ADEM), a postinfectious illness of the central
nervous system (CNS), is thought to be an autoimmune disease. Here, we characterized the …