Increased Rho kinase activity predicts worse cardiovascular outcome in ST-segment elevation myocardial infarction patients
X Li, X Wu, H Li, H Chen, Y Wang, W Li… - Cardiology …, 2016 - journals.viamedica.pl
Background: Few clinical studies have assessed Rho kinase (ROCK) in patients with
diabetes mellitus (DM) and ST-segment elevation myocardial infarction (STEMI). This study …
diabetes mellitus (DM) and ST-segment elevation myocardial infarction (STEMI). This study …
[HTML][HTML] Increased leukocyte Rho-kinase activity in a population with acute coronary syndrome
HW Hou, XG Li, M Yan, ZQ Hu… - Molecular Medicine …, 2013 - spandidos-publications.com
Accumulating evidence suggests that Rho-associated kinase (ROCK) may be important in
the pathogenesis of atherosclerosis and coronary vasospasm. In the present study, we …
the pathogenesis of atherosclerosis and coronary vasospasm. In the present study, we …
Enhanced Rho-kinase activity: pathophysiological relevance in type 2 diabetes
L Liu, L Tan, J Lai, S Li, DW Wang - Clinica chimica acta, 2016 - Elsevier
Background Accumulating evidence indicates that Rho-associated kinase (ROCK) has been
involved in the pathogenesis of insulin resistance and diabetes. However, little clinical …
involved in the pathogenesis of insulin resistance and diabetes. However, little clinical …
A combination of increased Rho kinase activity and N-terminal pro-B-type natriuretic peptide predicts worse cardiovascular outcome in patients with acute coronary …
Background Recent experimental evidence suggests that the Rho/Rho-kinase (ROCK)
system may play an important role in the pathogenesis of acute coronary syndrome (ACS) …
system may play an important role in the pathogenesis of acute coronary syndrome (ACS) …
[HTML][HTML] Rho kinase cascade activation in circulating leukocytes in patients with diabetes mellitus type 2
MP Ocaranza, P Valderas, J Moya, L Gabrielli… - Cardiovascular …, 2020 - Springer
Background The intracellular ROCK signaling pathway is an important modulator of blood
pressure and of cardiovascular and renal remodeling when Rho-kinase activity is increased …
pressure and of cardiovascular and renal remodeling when Rho-kinase activity is increased …
Increased Rho kinase activity in a Taiwanese population with metabolic syndrome
Objectives: We sought to determine whether Rho kinase (ROCK) activity is increased in a
Taiwanese population with metabolic syndrome (MetS). Background: Recent studies …
Taiwanese population with metabolic syndrome (MetS). Background: Recent studies …
Mechanisms of favorable effects of Rho kinase inhibition on myocardial remodeling and systolic function after experimental myocardial infarction in the rat
C Mera, I Godoy, R Ramírez, J Moya… - Therapeutic …, 2016 - journals.sagepub.com
Objective: The objective of this study was to determine the molecular mechanisms by which
cardiac Rho-associated coiled-coil containing protein kinase (ROCK) activation after …
cardiac Rho-associated coiled-coil containing protein kinase (ROCK) activation after …
Rho-associated kinase activity is an independent predictor of cardiovascular events in acute coronary syndrome
M Kajikawa, K Noma, A Nakashima, T Maruhashi… - …, 2015 - Am Heart Assoc
Rho-associated kinases play an important role in a variety of cellular functions. Although
Rho-associated kinase activity has been shown to be an independent predictor for future …
Rho-associated kinase activity has been shown to be an independent predictor for future …
Increased Rho kinase activity in congestive heart failure
Aims Rho kinases (ROCKs) are the best characterized effectors of the small G‐protein
RhoA, and play a role in enhanced vasoconstriction in animal models of congestive heart …
RhoA, and play a role in enhanced vasoconstriction in animal models of congestive heart …
[HTML][HTML] The function of Rho-associated kinases ROCK1 and ROCK2 in the pathogenesis of cardiovascular disease
S Hartmann, AJ Ridley, S Lutz - Frontiers in pharmacology, 2015 - frontiersin.org
Rho-associated kinases ROCK1 and ROCK2 are serine/threonine kinases that are
downstream targets of the small GTPases RhoA, RhoB, and RhoC. ROCKs are involved in …
downstream targets of the small GTPases RhoA, RhoB, and RhoC. ROCKs are involved in …