Alkyl cyanoacrylates have been used as surgical materials, in particular as biodegradable
tissue adhesives, since the 1960s (Leonard et al., 1966). Since their discovery, the US Food …

The properties inherent in poly (alkylcyanoacrylate)(PACA) nanoparticles, such as
biocompatibility and biodegradability of the polymer, a simple preparation process and …

This review considers the use of poly (alkylcyanoacrylates)(PACAs) as biomedical materials.
We first present the different aspects of the polymerization of alkylcyanoacrylate monomers …

Poly (alkylcyanoacrylate)(PACA) nanoparticles were first developed 25 years ago taking
advantage of the in vivo degradation potential of the polymer and of its good acceptance by …

Nanoscale biodegradable polymeric structures such as nanoparticles, nanocapsules,
nanocoatings, and nanofibers have created various exciting perspectives in biomedical …

Abstract Poly (alkylcyanoacrylate)[PACA] nanoparticles have been studied since the early
1980s as possible colloidal drug delivery systems. Several excellent general reviews have …

First prepared in 1979, the colloidal nanoparticles based on biocompatible and bioerosive
poly (alkyl cyanoacrylate) materials are still under investigation and hold promise for the …

Nanoparticles developed from poly (alkyl cyanoacrylate)(PACA) biodegradable polymers
have opened new and exciting perspectives in the field of drug delivery due to their nearly …

Starting in the late 1970s, the pioneering work of Patrick Couvreur gave birth to the first
biodegradable nanoparticles composed of a biodegradable synthetic polymer. These …

The colloidal particles of poly (alkyl cyanoacrylate)(PACA) posses a great promise as drug
carrier systems for delivery of anticancer drugs, antibiotics and other pharmaceuticals. Such …