Gluconeogenic carbon metabolism is not well understood, especially within the context of
flux partitioning between energy generation and biomass production, despite the importance …

Abstract The transformation of 4-hydroxybenzoate (4-HBA) to protocatechuate (PCA) is
catalyzed by flavoprotein oxygenases known as para-hydroxybenzoate-3-hydroxylases …

Pseudomonas species thrive in different nutritional environments and can catabolize
divergent carbon substrates. These capabilities have important implications for the role of …

Two strains of Escherichia coli were engineered to accumulate pyruvic acid from two sugars
found in lignocellulosic hydrolysates by knockouts in the aceE, ppsA, poxB, and ldhA genes …

Background Given its high surplus and low cost, glycerol has emerged as interesting carbon
substrate for the synthesis of value-added chemicals. The soil bacterium Pseudomonas …

A Pseudomonas putida S12 strain was constructed that is able to convert glucose to p-
coumarate via the central metabolite l-tyrosine. Efficient production was hampered by …

Efficient cofermentation of d-glucose, d-xylose, and l-arabinose, three major sugars present
in lignocellulose, is a fundamental requirement for cost-effective utilization of lignocellulosic …

Fructose uptake in the soil bacterium Pseudomonas putida occurs through a canonical
phosphoenolpyruvate (PEP)-dependent sugar transport system (PTSFru). The logic of the …

Expansion of the burgeoning biofuels agenda involves not only the design of suitable
genetic and metabolic devices but also their deployment into suitable hosts that can endure …

To broaden the substrate scope of microbial cell factories towards renewable substrates,
rational genetic interventions are often combined with adaptive laboratory evolution (ALE) …