Inflammation has been increasingly recognized as an important pathological component of
heart failure. Existing methods of assessing myocardial infiltrate are labor-intensive and …

Recent recognition that an autoimmune myocarditis may precede, and result in, dilated
cardiomyopathy has focused attention on immune mechanisms of myocardial injury. In this …

Immune mediators play a critical role in the pathogenesis and outcomes of a number of
cardiac diseases. This review summarizes recent findings on the composition of the …

Dilated cardiomyopathy (DCM) is a heterogeneous group of myocardial diseases clinically
defined by the presence of left ventricular dilatation and contractile dysfunction. Among …

Clinical and experimental studies have recently highlighted the importance of immune-
mediated mechanisms in the pathogenesis of cardiovascular diseases. The manifestations …

This review focuses on autoimmune myocarditis and its sequela, inflammatory dilated
cardiomyopathy (DCMI), and the inflammatory and immune mechanisms underlying the …

Experimental and clinical data suggest a relationship between myocarditis and dilated
cardiomyopathy. One postulated mechanism is a viral infection triggering a host response …

OBJECTIVE: To determine whether immunohistochemical analysis of cardiac biopsies from
patients presenting clinically as dilated cardiomyopathy (DCM) show a chronic inflammatory …

Heart failure has become an increasingly prevalent disorder with considerable morbidity
and mortality. While many causal mechanisms such as inherited cardiomyopathies …

Background We used a murine model of autoimmune myocarditis to investigate
systematically whether serum markers of myocardial cell injury, that is, cardiac troponin T …