Association of genetic polymorphisms in PRKDC and XRCC4 with risk of ESCC in a high-incidence region of North China

HL Yang, DD Qiao, K Li, XL Cheng, J Yang… - Tumori …, 2016 - journals.sagepub.com
Background The nonhomologous end-joining (NHEJ) pathway is the main mechanism
repairing DNA double-strand breaks (DSBs) in human cells. This research was designed to …

Association of the genetic polymorphisms in XRCC6 and XRCC5 with the risk of ESCC in a high-incidence region of North China

K Li, X Yin, H Yang, J Yang, J Zhao, C Xu… - Tumori …, 2015 - journals.sagepub.com
Background The XRCC6 and XRCC5 genes are part of the nonhomologous end-joining
(NHEJ) pathway, which is the main mechanism repairing DNA double-strand breaks (DSBs) …

DNA repair gene XRCC1 polymorphisms and non-Hodgkin lymphoma risk in a Chinese population

J Liu, B Song, Z Wang, X Song, Y Shi, J Zheng… - Cancer genetics and …, 2009 - Elsevier
Genetic polymorphism in DNA repair genes may influence individual variation in DNA repair
capacity, which may be associated with cancer risks. This hospital-based case–control study …

DNA repair gene XRCC3 polymorphisms and cancer risk: a meta-analysis of 48 case–control studies

S Han, HT Zhang, Z Wang, Y Xie, R Tang… - European journal of …, 2006 - nature.com
The X-ray repair cross-complementing group 3 (XRCC3) is a highly suspected candidate
gene for cancer susceptibility. However, association studies on the XRCC3 polymorphisms …

Three polymorphisms of DNA repair gene XRCC1 and the risk of glioma: a case–control study in northwest China

G Xu, M Wang, W Xie, X Bai - Tumor Biology, 2014 - Springer
Three polymorphisms of X-ray repair cross-complementing groups 1 (XRCC1) Arg194Trp,
Arg280His, and Arg399Gln may be associated with the individual susceptibility to glioma …

An investigation on the polymorphisms of two DNA repair genes and susceptibility to ESCC and GCA of high-incidence region in northern China

N Wang, X Dong, R Zhou, W Guo, X Zhang… - Molecular biology reports, 2009 - Springer
Aim To investigate the possible association of three SNPs, XRCC2 C41657T, XRCC2
G4234C and XRCC3 A17893G with susceptibility to esophageal squamous cell carcinoma …

The Thr241Met polymorphism in the XRCC3 gene is associated with increased risk of cancer in Chinese mainland populations

L Du, T Xiong, Q He, Y Wang, J Shen, Y Peng, Q Jia… - Tumor Biology, 2014 - Springer
Abstract The Thr241Met polymorphism in XRCC3 gene may affect the DNA repair pathways
and be associated with the risk of cancer. However, the results of previous studies are …

Genetic polymorphisms in the DNA repair gene XRCC1 and susceptibility to glioma in a Han population in northeastern China: a case–control study

D Wang, Y Hu, H Gong, J Li, Y Ren, G Li, A Liu - Gene, 2012 - Elsevier
BACKGROUND: Several single nucleotide polymorphisms (SNPs) in the X-ray cross-
complementing group 1 (XRCC1) gene have been shown to influence DNA repair and to …

[PDF][PDF] Polymorphisms in DNA repair gene XRCC1 and increased genetic susceptibility to glioma

XB Hu, Z Feng, YC Fan, ZY Xiong… - Asian Pac J Cancer …, 2011 - researchgate.net
Background: The XRCC1 gene encodes the XRCC1 protein, which complexes with three
other DNA repair enzymes involved in the base-excision repair (BER) pathways. Different …

Association between polymorphisms in DNA repair gene XRCC1 and non-melanoma skin cancer risk: a meta-analysis

L Wang, J Xu, B Duan - OncoTargets and therapy, 2017 - Taylor & Francis
Objective Non-melanoma skin cancer (NMSC) is the most common malignancy with
annually rising incidence. The aim of this study was to estimate the association between …