The identification of behavioral traits that could predict an individual's susceptibility to
engage in cocaine addiction is relevant for understanding and preventing this disorder, but …

Anxiety disorders and substance use disorders are strongly associated in humans.
Accordingly, a widely held but controversial concept in the addiction field, the so-called “self …

The expression phase of cocaine-induced conditioned place preference (CPP) represents a
cocaine-seeking behavior triggered by contextual cues associated with the rewarding effects …

Men and women respond differently to the subjective effects of cocaine and cocaine-
associated cues, which has implications for the development and maintenance of cocaine …

Clinical studies demonstrate that anxiety disorders increase the risk of substance use
disorder. However, few studies have directly assessed anxiety as a vulnerability factor in …

Neural and physiological factors underlying individual differences in the vulnerability to drug
abuse are the major questions remained to be determined. The present study described …

The development and maintenance of cocaine addiction depend heavily on learned reward-
environment associations that can induce drug-seeking behavior and relapse …

Some clinical studies have shown that anxiety disorders are often associated with drug
dependence, although it remains unclear whether these disorders are primary or secondary …

The environment in which cocaine is experienced becomes associated with the effects of the
drug and can then elicit cocaine craving. This study examined whether the hippocampus is …

Rationale Age of initial exposure to addictive substances is inversely proportional to risk of
developing drug dependence. There is debate, however, as to whether intake at a young …