[HTML][HTML] Three-dimensional microtubule behavior in Xenopus egg extracts reveals four dynamic states and state-dependent elastic properties

PJ Keller, F Pampaloni, G Lattanzi, EHK Stelzer - Biophysical Journal, 2008 - cell.com
Although microtubules are key players in many cellular processes, very little is known about
their dynamic and mechanical properties in physiological three-dimensional environments …

Structural Transitions at Microtubule Ends Correlate with Their Dynamic Properties in Xenopus Egg Extracts

I Arnal, E Karsenti, AA Hyman - The Journal of cell biology, 2000 - rupress.org
Microtubules are dynamically unstable polymers that interconvert stochastically between
growing and shrinking states by the addition and loss of subunits from their ends. However …

Microtubule dynamics: an interplay of biochemistry and mechanics

GJ Brouhard, LM Rice - Nature reviews Molecular cell biology, 2018 - nature.com
Microtubules are dynamic polymers of αβ-tubulin that are essential for intracellular
organization, organelle trafficking and chromosome segregation. Microtubule growth and …

Analysis of microtubule polymerization in vitro and during the cell cycle in Xenopus egg extracts

PP Budde, A Desai, R Heald - Methods, 2006 - Elsevier
Microtubules are dynamic polymers that participate in multiple cellular processes such as
vesicular transport and cell division. Microtubule dynamics alter dramatically during the cell …

Microtubule bending and breaking in living fibroblast cells

DJ Odde, L Ma, AH Briggs, A DeMarco… - Journal of cell …, 1999 - journals.biologists.com
Microtubules in living cells frequently bend and occasionally break, suggesting that
relatively strong forces act on them. Bending implies an increase in microtubule lattice …

[HTML][HTML] Differences in intrinsic tubulin dynamic properties contribute to spindle length control in Xenopus species

WG Hirst, A Biswas, KK Mahalingan, S Reber - Current Biology, 2020 - cell.com
The function of cellular organelles relates not only to their molecular composition but also to
their size. However, how the size of dynamic mesoscale structures is established and …

Modern methods to interrogate microtubule dynamics

M Bailey, L Conway, MW Gramlich… - Integrative …, 2013 - academic.oup.com
Microtubules are essential protein filaments required to organize and rearrange the interior
of the cell. They must be stiff with mechanical integrity to support the structure of the cell. Yet …

Determination of microtubule dynamic instability in living cells

K Kamath, E Oroudjev, MA Jordan - Methods in cell biology, 2010 - Elsevier
The precise regulation of microtubules and their dynamics is critical for cell cycle
progression, cell signaling, intracellular transport, cell polarization, and organismal …

[HTML][HTML] Microtubule growth rates are sensitive to global and local changes in microtubule plus-end density

ZM Geisterfer, DY Zhu, TJ Mitchison, J Oakey, JC Gatlin - Current Biology, 2020 - cell.com
The microtubule cytoskeleton plays critically important roles in numerous cellular functions
in eukaryotes, and it does so across a functionally diverse and morphologically disparate …

Microtubule dynamics in Xenopus egg extracts

M Shirasu, A Yonetani… - Microscopy research and …, 1999 - Wiley Online Library
The organization and function of microtubules change dramatically during the cell cycle. At
the onset of mitosis, a radial array of microtubules is broken down and reorganized into a …