Medical nanoparticle impact on macrophage temporal dry mass development quantified in vitro by digital holographic microscopy

K Eder, A Marzi, Á Barroso, B Kemper… - … Phase Imaging VII, 2021 - spiedigitallibrary.org
Quantitative phase imaging (QPI) has been demonstrated to be a versatile tool for minimally
invasive label-free imaging of biological specimens and time-resolved cellular analysis. In …

[HTML][HTML] Label-free digital holographic microscopy for in vitro cytotoxic effect quantification of organic nanoparticles

KM Eder, A Marzi, Á Barroso, S Ketelhut, B Kemper… - Cells, 2022 - mdpi.com
Cytotoxicity quantification of nanoparticles is commonly performed by biochemical assays to
evaluate their biocompatibility and safety. We explored quantitative phase imaging (QPI) …

Utilizing quantitative phase imaging with digital holographic microscopy for characterization of nanomaterial-induced tissue alterations

A Ntovas, Á Barroso, K Eder, S Ketelhut… - … Phase Imaging VIII, 2022 - spiedigitallibrary.org
We explored the capabilities of quantitative phase imaging (QPI) with digital holographic
microscopy (DHM) to quantify nanoparticle-induced tissue alterations and the performance …

Multimodal label-free growth and morphology characterization of different cell types in a single culture with quantitative digital holographic phase microscopy

B Kemper, J Wibbeling, L Kastl… - Quantitative Phase …, 2015 - spiedigitallibrary.org
For the analysis of the impact of pharmaceuticals or pathogens on different cellular
phenotypes under identical measurement conditions and to analyze interactions between …

Morphological alterations in primary hepatocytes upon nanomaterial incubation assessed by digital holographic microscopy and holotomography

K Eder, A Marzi, M Wiemann, U Rauen… - … Phase Imaging VIII, 2022 - spiedigitallibrary.org
Significant improvements in quantitative phase imaging (QPI) technologies established
digital holographic microscopy (DHM) and holotomography (HT) as tools for label-free …

Fast imaging of cardiomyocyte dynamics alterations after drug treatment utilizing quantitative phase digital holographic microscopy

B Kemper, S Ketelhut, I Stojanovic… - … Phase Imaging VI, 2020 - spiedigitallibrary.org
Digital holographic microscopy (DHM) is an interferometry-based variant of quantitative
phase microscopy (QPM) that can be integrated modular into various common microscopes …

Digital holographic microscopy overcomes the limitations of in vitro nanomaterial cytotoxicity testing

S Mues, S Ketelhut, B Kemper… - … Phase Imaging III, 2017 - spiedigitallibrary.org
The cytotoxic potential of nanomaterials is commonly evaluated by different cellular
endpoints as reactive oxygen species formation, cell viability or cell death. Usually these …

[HTML][HTML] Quantitative phase imaging for label-free analysis of cancer cells—focus on digital holographic microscopy

Z El-Schich, A Leida Mölder, A Gjörloff Wingren - Applied Sciences, 2018 - mdpi.com
To understand complex biological processes, scientists must gain insight into the function of
individual living cells. In contrast to the imaging of fixed cells, where a single snapshot of the …

Label-free detection of global morphology changes in confluent cell layers utilizing quantitative phase imaging with digital holographic microscopy

B Kemper, L Pohl, M Kaiser, E Döpker… - … on Biomedical Optics, 2019 - opg.optica.org
For the example of digital holographic microscopy (DHM), a variant of quantitative phase
imaging (QPI), we explored strategies for the analysis of confluent cell layers utilizing …

Label-free quantitative in vitro live cell imaging with digital holographic microscopy

B Kemper, A Bauwens, D Bettenworth, M Götte… - Label-Free Monitoring of …, 2019 - Springer
Label-free quantitative in vitro imaging of living cell cultures with light microscopy is an
important tool for various research fields in the life sciences. Digital holographic microscopy …