There is no hiding if you Seq: recent breakthroughs in Pseudomonas aeruginosa research revealed by genomic and transcriptomic next-generation sequencing

RXE Valli, M Lyng… - Journal of medical …, 2020 - microbiologyresearch.org
The advent of next-generation sequencing technology has revolutionized the field of
prokaryotic genetics and genomics by allowing interrogation of entire genomes …

[HTML][HTML] What It Takes to Be a Pseudomonas aeruginosa? The Core Genome of the Opportunistic Pathogen Updated

B Valot, C Guyeux, JY Rolland, K Mazouzi, X Bertrand… - PloS one, 2015 - journals.plos.org
Pseudomonas aeruginosa is an opportunistic bacterial pathogen able to thrive in highly
diverse ecological niches and to infect compromised patients. Its genome exhibits a mosaic …

Which microbial factors really are important in Pseudomonas aeruginosa infections?

A Crousilles, E Maunders, S Bartlett, C Fan… - Future …, 2015 - Future Medicine
Over the last two decades, tens of millions of dollars have been invested in understanding
virulence in the human pathogen, Pseudomonas aeruginosa. However, the top 'hits' …

[HTML][HTML] Clinical utilization of genomics data produced by the international Pseudomonas aeruginosa consortium

L Freschi, J Jeukens, I Kukavica-Ibrulj, B Boyle… - Frontiers in …, 2015 - frontiersin.org
The International Pseudomonas aeruginosa Consortium is sequencing over 1000 genomes
and building an analysis pipeline for the study of Pseudomonas genome evolution, antibiotic …

[HTML][HTML] Keeping an eye on P. aeruginosa

SJ Salter - Nature Reviews Microbiology, 2015 - nature.com
Keeping an eye on P. aeruginosa | Nature Reviews Microbiology Skip to main content Thank
you for visiting nature.com. You are using a browser version with limited support for CSS. To …

Comparative genomic analysis of Pseudomonas aeruginosa virulence

DE Woods - Trends in microbiology, 2004 - cell.com
Recent work has signaled the beginning of the comparative genomics era for analysis of the
important pathogen Pseudomonas aeruginosa. Comprehensive systematization of …

Analysis of regulatory networks in Pseudomonas aeruginosa by genomewide transcriptional profiling

AL Goodman, S Lory - Current opinion in microbiology, 2004 - Elsevier
Transcriptional profiling using DNA microarrays has proved to be a valuable tool for
dissecting bacterial adaptation to various environments, including human hosts. Analysis of …

[HTML][HTML] Pseudomonas aeruginosa: An Audacious Pathogen with an Adaptable Arsenal of Virulence Factors

I Jurado-Martín, M Sainz-Mejías… - International journal of …, 2021 - mdpi.com
Pseudomonas aeruginosa is a dominant pathogen in people with cystic fibrosis (CF)
contributing to morbidity and mortality. Its tremendous ability to adapt greatly facilitates its …

BACTOME—a reference database to explore the sequence- and gene expression-variation landscape of Pseudomonas aeruginosa clinical isolates

K Hornischer, A Khaledi, S Pohl… - Nucleic acids …, 2019 - academic.oup.com
Extensive use of next-generation sequencing (NGS) for pathogen profiling has the potential
to transform our understanding of how genomic plasticity contributes to phenotypic …

[HTML][HTML] In-Vivo Expression Profiling of Pseudomonas aeruginosa Infections Reveals Niche-Specific and Strain-Independent Transcriptional Programs

P Bielecki, J Puchałka, ML Wos-Oxley, H Loessner… - PloS one, 2011 - journals.plos.org
Pseudomonas aeruginosa is a threatening, opportunistic pathogen causing disease in
immunocompromised individuals. The hallmark of P. aeruginosa virulence is its multi …