Emerging inhaled long-acting beta-2 adrenoceptor agonists for the treatment of COPD

TJ Monaco, NA Hanania - Expert opinion on emerging drugs, 2017 - Taylor & Francis
Introduction: Chronic obstructive pulmonary disease (COPD), characterized by persistent
and partially reversible airflow obstruction, is a leading cause of morbidity and mortality …

Investigational beta-2 adrenergic agonists for the treatment of chronic obstructive pulmonary disease

M Malerba, A Radaeli, P Montuschi… - Expert Opinion on …, 2017 - Taylor & Francis
Introduction: Long-acting bronchodilators are pivotal in the therapeutic management of
COPD patients with moderate-to-severe airflow obstruction. New ultra-long-acting β2 …

Therapeutic potential for novel ultra long-acting β2-agonists in the management of COPD: biological and pharmacological aspects

M Malerba, A Radaeli, JB Morjaria - Drug discovery today, 2012 - Elsevier
Chronic obstructive pulmonary disease (COPD) is characterised by progressive airflow
limitation. In moderate-to-severe COPD, long-acting bronchodilators are the basis of …

Long-acting β2-agonists (LABA) in chronic obstructive pulmonary disease: efficacy and safety

A Rossi, S Khirani, M Cazzola - International journal of chronic …, 2008 - Taylor & Francis
COPD is characterized by progressive airflow obstruction which does not fully reverse to
inhaled or oral pharmacotherapy. The management of patients with COPD has taken a …

Update on ultra-long-acting β agonists in chronic obstructive pulmonary disease

MA Zafar, C Droege, M Foertsch… - Expert opinion on …, 2014 - Taylor & Francis
Introduction: For the last two decades, long-acting β agonists (LABAs) have been a
cornerstone in the management of chronic obstructive pulmonary disease (COPD). They …

Bronchodilators-future role in the management of chronic obstructive pulmonary disease

M Rudolf, DP Tashkin - US Respiratory Disease, 2013 - elibrary.ru
Bronchodilators are central to the management of chronic obstructive pulmonary disease
(COPD). Recent therapeutic developments in COPD underscore a shift from short-acting …

[HTML][HTML] Long-acting beta-agonists in the management of chronic obstructive pulmonary disease: current and future agents

DP Tashkin, LM Fabbri - Respiratory research, 2010 - Springer
Chronic obstructive pulmonary disease (COPD) is characterized by progressive airflow
limitation and debilitating symptoms. For patients with moderate-to-severe COPD, long …

Ultra long-acting β-agonists in chronic obstructive pulmonary disease

RM Burkes, RJ Panos - Journal of Experimental Pharmacology, 2020 - Taylor & Francis
Introduction Inhaled β-agonists have been foundational medications for maintenance COPD
management for decades. Through activation of cyclic adenosine monophosphate …

Long‐acting beta2‐agonists for poorly reversible chronic obstructive pulmonary disease

S Appleton, P Poole, BJ Smith, A Veale… - Cochrane database …, 2006 - cochranelibrary.com
Background Chronic obstructive pulmonary disease (COPD) is characterised by partially
reversible airflow limitation. Many patients have little reversibility to short acting …

The safety of long-acting β2-agonists in the treatment of stable chronic obstructive pulmonary disease

ML Decramer, NA Hanania, JO Lötvall… - International journal of …, 2013 - Taylor & Francis
Background Inhaled long-acting bronchodilators are the mainstay of pharmacotherapy for
chronic obstructive pulmonary disease (COPD). Both the twice-daily long-acting β2 …