Effect of glucose and insulin on oxidized low-density lipoprotein phagocytosis by human monocytes: a pilot study
We assessed the effect of glucose and insulin on human monocytes. Monocytes were
isolated from 16 healthy obese and 10 lean healthy participants. Insulin sensitivity was …
isolated from 16 healthy obese and 10 lean healthy participants. Insulin sensitivity was …
Highly oxidized low-density lipoprotein does not facilitate platelet aggregation
A Miyazaki, T Uehara, Y Usami… - Journal of …, 2020 - journals.sagepub.com
Objective This study aimed to examine whether oxidized low-density lipoprotein (oxLDL)
facilitates platelet aggregation, which is one cause for development of cardiovascular …
facilitates platelet aggregation, which is one cause for development of cardiovascular …
Oxidized low-density lipoproteins stimulate adhesion of monocytes to endothelial cells.
XL Niu, XD Yan, ZG Guo - Zhongguo yao li xue bao= Acta …, 1997 - europepmc.org
Aim To study the effects of oxidized low-density lipoproteins (ox-LDL) on the adhesiveness
of monocytes to endothelial cells. Methods LDL was obtained from healthy human plasma …
of monocytes to endothelial cells. Methods LDL was obtained from healthy human plasma …
Serum ox-LDL level is reduced with the extent of stenosis in coronary arteries
Oxidized LDL (ox-LDL) lipoproteins are proposed as important modified particles triggering
pro-inflammatory events through receptor-mediated pathways. We evaluated the circulating …
pro-inflammatory events through receptor-mediated pathways. We evaluated the circulating …
Lymphocyte cytotoxicity of oxLDL in patients with atherosclerosis
MJ Mahmoudi, M Mahmoudi, F Siassi… - Iranian Journal of …, 2011 - iji.sums.ac.ir
Background: Atherosclerosis, a chronic inflammatory disease of the vessel wall is
characterized by local and systemic immune responses to a variety of antigens. Oxidized …
characterized by local and systemic immune responses to a variety of antigens. Oxidized …
Acute effects of oxidized low density lipoprotein on metabolic responses in macrophages
HE De Vries, E Ronken, JH Reinders… - The FASEB …, 1998 - Wiley Online Library
The immediate effects of oxidized low density lipoprotein (OxLDL) on the metabolic activity
of cultured macrophages (RAW 264.7) were studied using a microphysiometer …
of cultured macrophages (RAW 264.7) were studied using a microphysiometer …
A phagocytosis assay for oxidized low-density lipoprotein versus immunoglobulin G-coated microbeads in human U937 macrophages
DT Vance, J Dufresne, A Florentinus-Mefailoski… - Analytical …, 2016 - Elsevier
The human monocyte cell line U937 was differentiated into an adherent macrophage
phenotype using phorbol 12-myristate 13-acetate (PMA) to assay the phagocytosis of …
phenotype using phorbol 12-myristate 13-acetate (PMA) to assay the phagocytosis of …
[HTML][HTML] Oxidized low-density lipoprotein contributes to atherogenesis via co-activation of macrophages and mast cells
C Chen, DB Khismatullin - PloS one, 2015 - journals.plos.org
Oxidized low-density lipoprotein (OxLDL) is a risk factor for atherosclerosis, due to its role in
endothelial dysfunction and foam cell formation. Tissue-resident cells such as macrophages …
endothelial dysfunction and foam cell formation. Tissue-resident cells such as macrophages …
Increased uptake of LDL by oxidized macrophages is the result of an initial enhanced LDL receptor activity and of a further progressive oxidation of LDL
B Fuhrman, O Judith, S Keidar, L Ben-Yaish… - Free Radical Biology …, 1997 - Elsevier
Iron ions were recently shown to induce cellular lipid peroxidation in macrophages, and
these oxidized cells can convert native low-density lipoprotein (LDL) to oxidized LDL (Ox …
these oxidized cells can convert native low-density lipoprotein (LDL) to oxidized LDL (Ox …
Oxidized low density lipoprotein can reduce the pinocytic activity in cultured human endothelial cells as measured by cellular uptake of [14C] sucrose
T Børsum, T Henriksen, A Reisvaag - Atherosclerosis, 1985 - Elsevier
The effect of low density lipoprotein (LDL) on the pinocytic activity in human endothelial cells
in culture, as measured by the uptake of [14 C] sucrose, was studied. The cells were …
in culture, as measured by the uptake of [14 C] sucrose, was studied. The cells were …