Ventromedial arcuate nucleus communicates peripheral metabolic information to the suprachiasmatic nucleus
The arcuate nucleus (ARC) is crucial for the maintenance of energy homeostasis as an
integrator of long-and short-term hunger and satiety signals. The expression of receptors for …
integrator of long-and short-term hunger and satiety signals. The expression of receptors for …
Neuronal systems and circuits involved in the control of food intake and adaptive thermogenesis
With the still‐growing prevalence of obesity worldwide, major efforts are made to understand
the various behavioral, environmental, and genetic factors that promote excess fat gain …
the various behavioral, environmental, and genetic factors that promote excess fat gain …
Brain circuits regulating energy homeostasis
For decades, increasingly sophisticated methods have been designed to address the
problem of the involvement of the brain in the physiology of energy homeostasis and the …
problem of the involvement of the brain in the physiology of energy homeostasis and the …
Sensing the fuels: glucose and lipid signaling in the CNS controlling energy homeostasis
SD Jordan, AC Könner, JC Brüning - Cellular and molecular life sciences, 2010 - Springer
The central nervous system (CNS) is capable of gathering information on the body's
nutritional state and it implements appropriate behavioral and metabolic responses to …
nutritional state and it implements appropriate behavioral and metabolic responses to …
Direct modulation of GFAP-expressing glia in the arcuate nucleus bi-directionally regulates feeding
Multiple hypothalamic neuronal populations that regulate energy balance have been
identified. Although hypothalamic glia exist in abundance and form intimate structural …
identified. Although hypothalamic glia exist in abundance and form intimate structural …
Altered hypothalamic function in diet-induced obesity
LA Velloso, MW Schwartz - International journal of obesity, 2011 - nature.com
Energy homeostasis involves a complex network of hypothalamic and extra-hypothalamic
neurons that transduce hormonal, nutrient and neuronal signals into responses that …
neurons that transduce hormonal, nutrient and neuronal signals into responses that …
[HTML][HTML] Hormonal regulation of food intake
Our knowledge of the physiological systems controlling energy homeostasis has increased
dramatically over the last decade. The roles of peripheral signals from adipose tissue …
dramatically over the last decade. The roles of peripheral signals from adipose tissue …
Tracing from fat tissue, liver, and pancreas: a neuroanatomical framework for the role of the brain in type 2 diabetes
F Kreier, YS Kap, TC Mettenleiter… - …, 2006 - academic.oup.com
The hypothalamus uses hormones and the autonomic nervous system to balance energy
fluxes in the body. Here we show that the autonomic nervous system has a distinct …
fluxes in the body. Here we show that the autonomic nervous system has a distinct …
Remodeling of the arcuate nucleus energy-balance circuit is inhibited in obese mice
DEG McNay, N Briançon, MV Kokoeva… - The Journal of …, 2012 - Am Soc Clin Investig
In the CNS, the hypothalamic arcuate nucleus (ARN) energy-balance circuit plays a key role
in regulating body weight. Recent studies have shown that neurogenesis occurs in the adult …
in regulating body weight. Recent studies have shown that neurogenesis occurs in the adult …
The hardship of obesity: a soft-wired hypothalamus
TL Horvath - Nature neuroscience, 2005 - nature.com
Food intake and energy expenditure are determinants of metabolic phenotype and are
regulated by the CNS. Although humans have a well-balanced homeostatic feedback loop …
regulated by the CNS. Although humans have a well-balanced homeostatic feedback loop …