Fully-grown mammalian oocytes within healthy preovulatory follicles are arrested in the first
meiotic prophase until the gonadotropins surge in vivo. However, the means by which …

The guanine nucleotide-binding alpha S subunit (Gαs) is an important element of key
signaling pathways, which is widely expressed in mammalian tissues; however, its role in …

The mammalian ovarian follicle consists of a multilayered complex of somatic cells that
surround the oocyte. A signal from the follicle cells keeps the oocyte cell cycle arrested at …

Glutathione synthetase (GSS) catalyzes the final step in the synthesis of glutathione (GSH),
a well-established antioxidant. Research on the specific roles of the Gss gene during …

Immature stage VI Xenopus oocytes are arrested at the G2/M border of meiosis I until
exposed to progesterone, which induces meiotic resumption through a non‐genomic …

Maintenance of meiotic prophase arrest in fully grown vertebrate oocytes depends on an
elevated level of cAMP in the oocyte. To investigate how the cAMP level is regulated, we …

To investigate the effect of the antioxidant N-acetylcysteine (NAC) on the proliferation and
apoptosis in CG8005 gene-interfering Drosophila S2 embryonic cells by scavenging …

Glutathione (GSH) is a tripeptide thiol antioxidant that has been shown to be important to
overall reproductive health. Glutamate cysteine ligase, the rate-limiting enzyme in GSH …

Mammalian oocytes grow and undergo meiosis within ovarian follicles. Oocytes are arrested
at the first meiotic prophase, held in meiotic arrest by the surrounding follicle cells until a …

This study aims to investigate the effect as well as mechanism of ginsenoside Rg1 (Rg1) on
premature ovarian failure (POF) induced by d-galactose (d-gal) in mice. C57BL/6 female …