In mammalian growing follicles, oocytes are arrested at the diplotene stage (which
resembles the G2/M boundary in mitosis), while the granulosa cells (GCs) continue to …

Like somatic cells, mammalian spermatozoa appear to contain several different
heterotrimeric G protein α‐subunits that could mediate specialized cell responses. However …

The maintenance of meiotic prophase arrest in mouse oocytes within fully grown follicles,
prior to the surge of luteinizing hormone (LH) that triggers meiotic resumption, depends on a …

Several recent studies have suggested that resumption of oocyte meiosis, indicated by
germinal vesicle breakdown or GVBD, involves inhibition of endogenous heterotrimeric G …

Fertilization in mammals initiates “egg activation,” a series of events leading to embryo
development. The signal transduction events that occur as a result of sperm-egg interactions …

Embryo implantation is a complicated event that relies on two critical factors: the competent
blastocyst and the receptive uterus. Successful implantation results from tight coordination of …

Background: Ras dexamethasone-induced protein (RASD1) is a member of Ras superfamily
of small GTPases. RASD1 regulates various signaling pathways involved in iron …

Apoptosis plays a vital role in the developmental process of the mammalian reproduction
system, such as during folliculogenesis or spermatogenesis. Kinesin superfamily (Kif) …

For a sperm to successfully fertilize an egg, it must first undergo capacitation in the female
reproductive tract and later undergo acrosomal reaction (AR) upon encountering an egg …

Both genetic and microenvironmental detrimental factors are involved in ovarian
dysfunction, leading to the increasing rate of involuntary childlessness in recent years …