Comprehensive platelet phenotyping supports the role of platelets in the pathogenesis of acute venous thromboembolism–results from clinical observation studies

M Panova-Noeva, B Wagner, M Nagler, T Koeck… - …, 2020 - thelancet.com
Background The pathogenesis of arterial and venous thrombosis is in large part interlaced.
How much platelet phenotype relates to acute venous thromboembolism (VTE) independent …

The role of platelets in venous thromboembolism

S Montoro-García, M Schindewolf… - … in thrombosis and …, 2016 - thieme-connect.com
Multiple factors contribute to the risk of venous thromboembolism (VTE). Platelets have
attracted much interest in arterial cardiovascular disease, whereas their role in VTE has …

Platelet count and outcome in patients with acute venous thromboembolism

P Di Micco, N Ruiz-Giménez, JA Nieto… - Thrombosis and …, 2013 - thieme-connect.com
The relationship between platelet count and outcome in patients with acute venous
thromboembolism (VTE) has not been consistently explored. RIETE is an ongoing registry of …

Platelet function as a risk factor for venous thromboembolism in the Framingham Heart Study

MK Puurunen, SJ Hwang, CJ O'Donnell, G Tofler… - Thrombosis research, 2017 - Elsevier
Introduction The relationship of venous thromboembolism (VTE) with platelet reactivity is
unclear. Platelet function plays a key role in arterial thrombosis. Evidence suggests …

[HTML][HTML] Platelet subtypes in inflammatory settings

MA Hamad, K Krauel, N Schanze, N Gauchel… - Frontiers in …, 2022 - frontiersin.org
In addition to their essential role in hemostasis and thrombosis, platelets also modulate
inflammatory reactions and immune responses. This is achieved by specialized surface …

Platelet activation markers in evaluation of thrombotic risk factors in various clinical settings

M Kannan, F Ahmad, R Saxena - Blood reviews, 2019 - Elsevier
Platelets play a major role in primary hemostasis and thrombus formation. After vascular
injury, platelets adhere to injured site and rapidly change their shape that switches the …

Beyond Virchow's Triad: Does cardiovascular inflammation explain the recurrent nature of venous thromboembolism?

G Piazza - Vascular Medicine, 2015 - journals.sagepub.com
Piazza 103 the Atherosclerosis Risk In Communities (ARIC) Study, followed for incident DVT
or PE over 8.3 years, CRP above the 90th percentile was associated with a 76% increase in …

Potential of multidimensional, large-scale biodatabases to elucidate coagulation and platelet pathways as an approach towards precision medicine in thrombotic …

M Panova-Noeva, L Eggebrecht… - …, 2019 - thieme-connect.com
Cardiovascular and especially thrombotic diseases remain a major cause of morbidity and
mortality worldwide. In past years, significant improvements in understanding disease …

Platelet extracellular vesicles as biomarkers for arterial thrombosis

A Gasecka, AN Böing, KJ Filipiak, R Nieuwland - Platelets, 2017 - Taylor & Francis
Arterial thrombosis is a major and global cause of human death and disability. Considering
the socioeconomic costs of arterial thrombosis, identification of biomarkers to predict and …

The mean platelet volume is decreased in patients diagnosed with venous thromboembolism in the emergency department

G Lippi, R Buonocore… - Seminars in thrombosis …, 2016 - thieme-connect.com
Platelets are small corpuscular elements, which play an essential role in hemostasis and
thrombosis. As active players in the thrombotic process, hyperactive platelets are involved in …