Background The pancreatic-and brain-derived hormone amylin promotes negative energy
balance and is receiving increasing attention as a promising obesity therapeutic. However …

Amylin is a pancreas-derived neuropeptide that acts in the central nervous system (CNS) to
reduce food intake. Much of the literature describing the anorectic effects of amylin are …

Amylin acts in the CNS to reduce feeding and body weight. Recently, the ventral tegmental
area (VTA), a mesolimbic nucleus important for food intake and reward, was identified as a …

Amylin is produced in the pancreas and the brain, and acts centrally to reduce feeding and
body weight. Recent data show that amylin can act in the ventral tegmental area (VTA) to …

The intake-and body weight-suppressive hormone amylin exerts effects on energy balance
control at a variety of nuclei within the brain, including sites that have been referred to in the …

The ability of amylin, a pancreatic β-cell-derived neuropeptide, to promote negative energy
balance has been ascribed to neural activation at the area postrema. However, despite …

Amylin is secreted by pancreatic beta-cells and is believed to be a physiological signal of
satiation. Amylin's effect on eating has been shown to be mediated via a direct action at the …

The pancreatic hormone amylin acts in the central nervous system (CNS) to decrease food
intake and body weight. We hypothesized that amylin action in the CNS promotes energy …

Amylin is a peptide hormone that is mainly known to be produced by pancreatic β-cells in
response to a meal but amylin is also produced by brain cells in discrete brain areas albeit …

Amylin plays an important role in the control of nutrient fluxes. It is cosecreted with insulin
and reduces eating by promoting meal-ending satiation. This effect seems to depend on a …