Kisspeptin binding to its G-protein-coupled receptor KISS1R (also known as GPR54), which
is expressed by gonadotropin-releasing hormone (GnRH) neurons, stimulates GnRH …

Kisspeptin binding to its cognate G protein-coupled receptor (GPR54, aka Kiss1R) in
gonadotropin-releasing hormone (GnRH) neurons stimulates peptide release and activation …

The obligatory role of kisspeptin (KISS1) and its receptor (KISS1R) in regulating the
hypothalamic-pituitary–gonadal axis, puberty and fertility was uncovered in 2003. In the few …

Kisspeptin signaling at the gonadotropin-releasing hormone (GnRH) neuron is now
relatively well characterized and established as being critical for the neural control of fertility …

Neurons that produce gonadotropin-releasing hormone (GnRH) reside in the basal
forebrain and drive reproductive function in mammals. Understanding the circuitry that …

The Kiss1 gene encodes a family of peptides called kisspeptins, which bind to the G protein-
coupled receptor GPR54. Kisspeptin (s) and its receptor are expressed in the forebrain, and …

Background: Kisspeptin and its cognate receptor GPR54 are the central driving forces in the
hypothalamus-pituitary-gonadal axis essential for sexual maturation and reproduction …

Kisspeptin is a neuropeptide that signals via a Gαq-coupled receptor, GPR54, in
gonadotropin-releasing hormone (GnRH) neurons and is essential for pubertal maturation …

Kisspeptins, which are products of the Kiss1 gene, and their receptor, GPR54, have
emerged as key players in the regulation of gonadotropin-releasing hormone (GnRH) …

Kisspeptin is a neuropeptide with a critical role in the function of the hypothalamic–pituitary–
gonadal (HPG) axis. Kisspeptin is produced by two major populations of neurons located in …