Sleep deprivation therapy (SDT), also referred to as “wake therapy,” is a robust, rapid-acting
(within 24–48 hours), noninvasive antidepressant treatment. First proposed by Schulte1 and …

Growing clinical evidence in support of the efficacy and safety of sleep deprivation (SD), and
its biological mechanisms of action suggest that this technique can now be included among …

Total sleep deprivation (TSD) for one whole night improves depressive symptoms in 40–
60% of treatments. The degree of clinical change spans a continuum from complete …

The short-term antidepressive effect of single sleep deprivation (SD) treatment has been
unanimously confirmed in a large number of studies. SD is most effective in patients with a …

Sleep deprivation is a useful therapeutic option in the treatment of depressive disorders,
especially in pharmacoresistant disorders. Its therapeutic efficacy in other indications has …

[Sleep deprivation as antidepressive treatment]. - Abstract - Europe PMC Sign in | Create an
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Is sleep deprivation useful in the treatment of depression? - Abstract - Europe PMC Sign in |
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Objective: The authors' goal was to test the hypothesis that the antidepressant effect of total
sleep deprivation can be maintained by initially avoiding sleep during a supposedly “critical” …

Objective To systematically review evidence on the efficacy and safety of sleep deprivation
(SD) as a treatment option for patients with unipolar or bipolar depression. Methods A …

To the Editor: I read with great interest the recent meta-analysis by Boland et al on
antidepressant effects of acute sleep deprivation. 1 These authors did a masterful job of …