Sleep deprivation (SD) induces a rapid amelioration of mood in about 60% of depressed
patients. After the next night of sleep, however, most patients experience a relapse. Previous …

Insomnia, excessive sleepiness, and fatigue are common symptoms in depressed patients.
Excessive sleepiness is associated with impairments in cognitive and motor tasks and has a …

In the management of depression, the role of sleep and sleep disturbances is important for
several reasons. The same neurotransmitter systems that regulate mood, interest, energy …

Background Sleep deprivation (SD) is an antidepressant intervention with multiple
administration formats that has been investigated primarily with uncontrolled clinical trials …

Major depressive disorder (MDD) is one of the most prevalent major medical conditions with
a lifetime and 12-month prevalence of 2%-16% and 8%, respectively, in the United States …

EARLY TO BED, early to rise, may be the new prescription for depression. Twenty-two years
ago, quite by chance, psychiatrists discovered that a night without sleep sometimes cured …

Total sleep deprivation (TSD) leads to an immediate amelioration of depressed mood in
approximately 70% of patients with the melancholic subtype of depression. The clinical utility …

Although there is a body of literature on the therapeutic efficacy of sleep deprivation (SD)
there are only a few investigations in which the relevance of antidepressive medication for …

Major depressive disorder is one of the most common psychiatric illnesses in the United
States, with an estimated lifetime prevalence of up to 17%. 1 Affected individuals are at high …