Introduction: Studies on the relation between aldosterone synthase-344 T/C polymorphism
and diabetic nephropathy showed controversial conclusions. This meta-analysis aimed to …

Background: Aldosterone synthase (CYP11B2) is crucial for aldosterone production, and
variations in its gene may influence type 2 diabetes mellitus (T2DM) development. This …

Aims: CYP11B2 gene encodes a key enzyme for the production of aldosterone. Our aim is to
investigate the association of–344T/C polymorphism with hypertension in Japanese men …

Predispositions to essential hypertension and cardiovascular diseases are possibly
associated with gene polymorphisms of the renin–angiotensin system. Gene polymorphisms …

Polymorphisms affecting the synthesis of aldosterone or its regulation may have effects on
blood pressure. For example, an autosomal dominant form of human hypertension …

Objectives: The aim of our study was to evaluate the relationship between aldosterone
synthase gene polymorphism and cardiac dimensions in essential hypertension …

A common polymorphism exists for the aldosterone synthase (CYP11B2) gene at position
344 (C-344-T). The 344-C allele has been associated with increased aldosterone synthase …

Objective To investigate the relationship of gene polymorphism of angiotension converting
enzyme (ACE), aldosterone synthase (CYP11B2) with essential hypertension (EH) and left …

Objective The aim of the present study was to investigate the association between a
polymorphism of the aldosterone synthase gene CYP11B2 and left ventricular structure and …

Aldosterone synthase gene is one of the candidate genes responsible for the effects of
aldosterone. In particular, there are some evidences concerning the influence of this gene …