Cell-to-cell communication between bone, cartilage and the synovial membrane is not fully
understood and it is only attributed to the diffusion of substances through the extracellular …

Objective This study investigated whether chondrocytes within the cartilage matrix have the
capacity to communicate through intercellular connections mediated by voltage-gated gap …

Gap junctions (GJs) formed by connexins (Cxs) play an important role in the intercellular
communication within most body tissues. In this paper, we focus on GJs and Cxs present in …

The distribution, expression, and functionality of gap junctions was examined in bovine
chondrocytes (BCs) isolated from mature articular cartilage. BC cells displayed …

Objective The development of chondrocytic cell lines has enabled the investigation of the
role of cellular phenotype and mechanisms in articular cartilage biology and …

Osteoarthritis (OA) is the most common joint disease and involves progressive degeneration
of articular cartilage. The aim of this study was to investigate if chondrocytes from human …

We have previously reported that articular chondrocytes in tissue contain long cytoplasmic
arms that physically connect two distant cells. Cell-to-cell communication occurs through …

Communication between osteoblasts, osteoclasts, and osteocytes is integral to their ability to
build and maintain the skeletal system and respond to physical signals. Various …

Summary Objective Connexin (Cx) 43 hemichannels play a role in mechanotransduction.
This study was undertaken in order to determine if Cx43 hemichannels were activated in rat …

Gap junctional intercellular communication (GJIC) mediated by connexins, in particular
connexin 43 (Cx43), plays important roles in regulating signal transmission among different …