Thrombosis, the localized clotting of blood that affects arterial or venous circulation, is one of
the leading causes of death worldwide. Arterial thrombosis is commonly initiated by vascular …

Thrombosis, both venous and arterial, is a major cause of morbidity and mortality worldwide.
Consequently, there is an ongoing search for new antithrombotic drugs, particularly novel …

Objective: To provide an overview of the current state of knowledge regarding the
physiology of hemostasis, the pathophysiology of thrombosis, and the pharmacology of …

Thrombosis is the collective term for diseases caused by the localized accumulation of
circulating blood elements within the vasculature that result in vessel occlusion …

Thromboembolic disorders are a major cause of morbidity and mortality. As knowledge of
the complex interactions between the vessel wall, platelets and coagulation and fibrinolytic …

Ischemic cardiovascular diseases represent the most common cause of mortality and
morbidity in the western world, and atherothrombosis occupies a central role in their …

Thrombosis is the condition where an imbalance in the homeostatic mechanism results in
unwanted intravascular thrombus formation. Imbalances in this highly regulated process of …

Thrombosis is the formation of potentially deadly blood clots in the artery (arterial
thrombosis) or vein (venous thrombosis). Since thrombosis is one of the main causes of …

Recent advances in our understanding of the contribution of thrombin generation to arterial
thrombosis and the role of platelets in venous thrombosis have prompted new treatment …

Cardiovascular diseases associated with intravascular thrombosis are the most common
cause of death in both developed and developing countries. Clinical and experimental …