Recent evidence derived from four independent methods indicates that an excess
triglyceride storage within skeletal muscle is linked to insulin resistance. Potential …

It has long been recognized that skeletal muscle can contain modest stores of triglyceride
and that this depot of fuel can make a major contribution to energy production during …

The composition and biochemistry of skeletal muscle are altered in obesity and type 2
diabetes mellitus (DM) as compared to nonobese individuals. In health, skeletal muscle has …

The inability of insulin to stimulate glucose metabolism in skeletal muscle is a classic
characteristic of type 2 diabetes, but this insulin resistance entails altered patterns of lipid …

▪ Abstract Skeletal muscle contains the majority of the body's glycogen stores and a similar
amount of readily accessible energy as intramyocellular triglyceride (imTG). While a number …

Mounting evidence indicates that elevated intramyocellular triacylglycerol concentrations
are associated with diminished insulin sensitivity in skeletal muscle. This lipid accumulation …

Intracellular triglyceride (TG) is an important energy source for skeletal muscle. However,
recent evidence suggests that if muscle contains abnormally high TG stores its sensitivity to …

In animal studies, increased amounts of triglyceride associated with skeletal muscle (mTG)
correlate with reduced skeletal muscle and whole body insulin action. The aim of this study …

The alarming increase in obesity and associated type 2 diabetes mellitus (T2DM) is a
paramount public health concern in developing countries. Skeletal muscle insulin resistance …

The present article addresses the hypothesis that disturbances in skeletal muscle fatty acid
handling in abdominal obesity and type 2 diabetes mellitus may play a role in the aetiology …