[HTML][HTML] Evaluation of the safety and immunogenicity of the oral inactivated multivalent enterotoxigenic Escherichia coli vaccine ETVAX in Bangladeshi adults in a …

M Akhtar, MI Chowdhury, TR Bhuiyan, J Kaim… - Vaccine, 2019 - Elsevier
The safety and immunogenicity of the second generation oral enterotoxigenic Escherichia
coli (ETEC) vaccine ETVAX, consisting of inactivated recombinant E. coli strains over …

Safety and immunogenicity of the oral, inactivated, enterotoxigenic Escherichia coli vaccine ETVAX in Bangladeshi children and infants: a double-blind, randomised …

F Qadri, M Akhtar, TR Bhuiyan… - The Lancet Infectious …, 2020 - thelancet.com
Summary Background Enterotoxigenic Escherichia coli causes diarrhoea, leading to
substantial mortality and morbidity in children, but no specific vaccine exists. This trial tested …

[HTML][HTML] Safety and immunogenicity of an improved oral inactivated multivalent enterotoxigenic Escherichia coli (ETEC) vaccine administered alone and together with …

A Lundgren, L Bourgeois, N Carlin, J Clements… - Vaccine, 2014 - Elsevier
Background We have developed a new oral vaccine against enterotoxigenic Escherichia
coli (ETEC), which is the most common cause of bacterial diarrhea in children in developing …

Comparative Safety and Immunogenicity of Two Attenuated Enterotoxigenic Escherichia coli Vaccine Strains in Healthy Adults

R McKenzie, AL Bourgeois, F Engstrom… - Infection and …, 2006 - Am Soc Microbiol
ABSTRACT A vaccine against enterotoxigenic Escherichia coli (ETEC) is needed to prevent
diarrheal illness among children in developing countries and at-risk travelers. Two live …

[HTML][HTML] Status of vaccine research and development for enterotoxigenic Escherichia coli

AL Bourgeois, TF Wierzba, RI Walker - Vaccine, 2016 - Elsevier
Enterotoxigenic Escherichia coli (ETEC) is one of the most common bacterial causes of
diarrhea-associated morbidity and mortality, particularly among infants and young children …

Mucosal Immune Responses Against an Oral Enterotoxigenic Escherichia coli Vaccine Evaluated in Clinical Trials

AM Svennerholm, A Lundgren, S Leach… - The Journal of …, 2021 - academic.oup.com
Enterotoxigenic Escherichia coli (ETEC) is a leading cause of mortality and morbidity in
children in low-income countries. We have tested an oral ETEC vaccine, ETVAX, consisting …

Safety and immunogenicity of an oral, inactivated enterotoxigenic Escherichia coli plus cholera toxin B subunit vaccine in Bangladeshi adults and children

F Qadri, C Wennerås, F Ahmed, M Asaduzzaman… - Vaccine, 2000 - Elsevier
We have compared the B cell responses evoked in Bangladeshi, adults (n= 11, median age
25 years) and children (n= 21, median age 4.5 years), 7 days after intake of each of two …

Safety and immunogenicity of an oral, inactivated enterotoxigenic Escherichia coli plus cholera toxin B subunit vaccine in Bangladeshi children 18–36 months of age

F Qadri, T Ahmed, F Ahmed, RB Sack, DA Sack… - Vaccine, 2003 - Elsevier
A phase II safety and immunogenicity study of an oral-formalin inactivated enterotoxigenic
Escherichia coli (ETEC) vaccine containing six colonization factors (CFA/I, CS1, CS2, CS3 …

[HTML][HTML] Induction of mucosal and systemic immune responses against the common O78 antigen of an oral inactivated ETEC vaccine in Bangladeshi children and …

AM Svennerholm, F Qadri, A Lundgren, J Kaim… - Vaccine, 2022 - Elsevier
We tested an oral enterotoxigenic Escherichia coli (ETEC) vaccine, ETVAX, consisting of
inactivated E. coli overexpressing the most prevalent ETEC colonization factors (CFs) and a …

[HTML][HTML] Safety, tolerability, and immunogenicity of an oral inactivated ETEC vaccine (ETVAX®) with dmLT adjuvant in healthy adults and children in Zambia: An age …

N Sukwa, C Mubanga, LM Hatyoka… - Vaccine, 2023 - Elsevier
Abstract Background Enterotoxigenic Escherichia coli (ETEC) is an important cause of
moderate to severe diarrhoea in children for which there is no licensed vaccine. We …