Seizures are important neurological complications after traumatic brain injury (TBI) and are
reported for up to 50% of patients with TBI. Despite several studies, no drug strategy has …

Posttraumatic epilepsy (PTE) is a long-term negative consequence of traumatic brain injury
(TBI) in which recurrent spontaneous seizures occur after the initial head injury. PTE …

Objective To determine the role of aquaporin‐4 (AQP4) in posttraumatic epileptogenesis
using long‐term video‐electroencephalographic (vEEG) recordings. Here, differences in …

During injury to the central nervous system (CNS), astrocytes and microglia proliferate and
migrate around the lesion sites. Recently, it has been reported that one of the water …

After traumatic brain injury (TBI), multiple ongoing processes contribute to worsening and
spreading of the primary injury to create a secondary injury. One major process involves …

Micro traumatic brain injury (TBI) is the most common type of brain injury, but the
mechanisms underlying it are poorly understood. Aquaporin-4 (AQP4) is a water channel …

The water channel aquaporin-4 (AQP4) is important in brain water homeostasis, and is also
involved in astrocyte growth and glial scar formation. It has been reported that AQP4 …

Aquaporin-4 (AQP4) is expressed in astrocytes throughout the central nervous system,
particularly at the blood–brain and brain–cerebrospinal fluid barriers. Phenotype analysis of …

Brain edema following traumatic brain injury (TBI) is associated with considerable morbidity
and mortality. Prior indirect evidence has suggested the involvement of astrocyte water …

Atrophy of upper motor neurons hampers axonal regeneration and functional recovery
following spinal cord injury (SCI). Apart from the severity of primary injury, a series of …