Acute myeloid leukemia (AML) represents a group of clonal hematopoietic stem cell
disorders that is characterized by both failure to differentiate and over proliferation of the …

The evolution of acute myeloid leukemia (AML) classification reflects greater understanding
of the AML pathogenesis. The 2008 World Health Organization classification incorporated …

Detection of chromosomal abnormalities by cytogenetic analysis is critical in diagnosis and
therapeutic decision-making in AML. Detection of t (8; 21)(q22; q22. 1), inv (16)(p13. 1; …

The pathogenesis of acute myeloid leukaemias (AML) frequently requires at least 3
mutations in different cellular pathways. In many cases, mutations in proliferation/survival …

Objective: To study the frequency of mutations that may lead to a good or bad prognosis, as
well as their relation with the karyotype and immunophenotype in patients with acute …

Acute myeloid leukemia (AML) is a clonal malignancy characterized by ineffective
hematopoiesis. Most AML patients present different cytogenetic and molecular defects …

Introduction-About 25% of persons with new-diagnosed acute myeloid leukemia (AML) have
normal cytogenetics and no NPM1 or FLT3-ITD mutation. The prognosis and best therapy of …

Acute myeloid leukemia (AML) can be grouped into morphologically or genetically defined
subtypes. Today, the AML phenotype–genotype associations, that is, FAB/WHO (French …

A comparative study on the differential diagnosis of acute myeloid leukaemia based on
French American British Cooperative Group (FAB) and World Health Organization (WHO) …

Acute myeloid leukemia (AML) is a heterogeneous group of disorders that can be
discriminated by morphology, immunophenotyping or more recently by cytogenetic and …