High expression of estrogen-related receptor α is significantly associated with poor prognosis in patients with colorectal cancer

R Liang, Y Lin, CL Yuan, ZH Liu, YQ Li… - Oncology …, 2018 - spandidos-publications.com
Colorectal cancer (CRC) is one of the most common types of malignancy with high morbidity
and mortality rates worldwide. This biologically heterogeneous disease results in diverse …

Oestrogen receptor-related receptor alpha (ERRα) and oestrogen receptors (ERα and ERβ) exhibit different gene expression in human colorectal tumour progression

A Cavallini, M Notarnicola, R Giannini… - European journal of …, 2005 - Elsevier
We have investigated the presence of oestrogen receptor-related (ERR) mRNA in human
colorectal tumour tissues and adjacent normal mucosa by reverse transcriptase and nested …

Combined estrogen alpha and beta receptor expression has a prognostic significance for colorectal cancer patients

G Topi, S Ghatak, SR Satapathy, R Ehrnström… - Frontiers in …, 2022 - frontiersin.org
We reported that high estrogen receptor beta (ERβ) expression is independently associated
with better prognosis in female colorectal cancer (CRC) patients. However, estrogen …

[HTML][HTML] Association of the oestrogen receptor beta with hormone status and prognosis in a cohort of female patients with colorectal cancer

G Topi, R Ehrnström, K Jirström, I Palmquist… - European journal of …, 2017 - Elsevier
Background The oestrogen receptor beta (ERβ) is the predominant oestrogen receptor in
the normal colon mucosa and has been reported to exert anti-proliferative and pro-apoptotic …

High Oestrogen receptor alpha expression correlates with adverse prognosis and promotes metastasis in colorectal cancer

G Topi, SR Satapathy, S Ghatak, K Hellman… - Cell Communication and …, 2024 - Springer
In normal colon tissue, oestrogen receptor alpha (ERα) is expressed at low levels, while
oestrogen receptor beta (ERβ) is considered the dominant subtype. However, in colon …

[HTML][HTML] Expression of estrogen receptor β in human colorectal cancer

LQ Xie, JP Yu, HS Luo - World Journal of Gastroenterology, 2004 - ncbi.nlm.nih.gov
AIM: To determine the expression of estrogen receptor (ER) β in Chinese colorectal
carcinoma (CRC) patients. METHODS: ERβ expression in CRC was investigated by …

Expression of estrogen receptor and progesterone receptor in colorectal cancer: a quantitative study

ZW Zhou, DS Wan, GQ Wang, ZZ Pan… - Ai zheng= Aizheng …, 2004 - europepmc.org
Methods ER and PR expression in cytoplasm and nucleus of tumor tissues and normal
mucosas from 45 colorectal cancer patients were quantitatively measured using radioligand …

Function of estrogen-related receptor α in human endometrial cancer

A Watanabe, Y Kinoshita, K Hosokawa… - The Journal of …, 2006 - academic.oup.com
Introduction: The estrogen-related receptor α (ERRα) is an orphan member of the nuclear
receptor superfamily that is closely related to estrogen receptor α (ERα). ERRα binds an …

Estrogen receptor β expression and colorectal cancer: a systematic review and meta-analysis

Y Niv - European journal of gastroenterology & hepatology, 2015 - journals.lww.com
Background Estrogen receptor β (ERβ) is a potential tumor-suppressor gene in colorectal
cancer (CRC). This hypothesis is supported by clinical and laboratory observations. Aim In …

Expression of estrogen receptor (ER) subtypes and ERβ isoforms in colon cancer

M Campbell-Thompson, IJ Lynch, B Bhardwaj - Cancer research, 2001 - AACR
Colon cancer incidence and mortality rates are lower in females compared with males, and
numerous epidemiological studies suggest that estrogen replacement therapy (ERT) …