[HTML][HTML] MicroRNA-21 inhibition suppresses alveolar M2 macrophages in an ovalbumin-induced allergic asthma mice model
Purpose MicroRNA-21 (miR-21) influences the Th2 immune pathway by suppressing the
expressions of interleukin (IL)-12 and interferon (IFN)-γ. The effects of miR-21 suppression …
expressions of interleukin (IL)-12 and interferon (IFN)-γ. The effects of miR-21 suppression …
Inhibition of MicroRNA-21 by an antagomir ameliorates allergic inflammation in a mouse model of asthma
ABSTRACT Aim of the Study: MicroRNA-21 (miR-21) is up-regulated during allergic airway
inflammation, reflecting a Th2 immune response. We investigated the effects of an miR-21 …
inflammation, reflecting a Th2 immune response. We investigated the effects of an miR-21 …
MicroRNA-21 inhibits toll-like receptor 2 agonist–induced lung inflammation in mice
SR Case, RJ Martin, D Jiang, MN Minor… - Experimental lung …, 2011 - Taylor & Francis
Impaired airway innate immunity (eg, suppressed Toll-like receptor 2 [TLR2] signaling) has
been reported in allergic lungs with bacterial infection. Recently, an allergic mouse lung …
been reported in allergic lungs with bacterial infection. Recently, an allergic mouse lung …
MicroRNA-29 mediates anti-inflammatory effects and alleviation of allergic responses and symptoms in mice with allergic rhinitis
J Wang, J Yin, H Peng, A Liu - Allergy, Asthma & Clinical Immunology, 2021 - Springer
Background To investigate the role of microRNA-29 (miR-29) in mice with allergic rhinitis
(AR) and its underlying mechanism. Methods AR model was established in BALB/c mice by …
(AR) and its underlying mechanism. Methods AR model was established in BALB/c mice by …
miR-31 attenuates murine allergic rhinitis by suppressing interleukin-13-induced nasal epithelial inflammatory responses
F Zhou, P Liu, H Lv, Z Gao… - Molecular medicine …, 2021 - spandidos-publications.com
The present study aimed to investigate whether microRNA (miR)‑31 exerted therapeutic
potential in allergic rhinitis (AR) and to explore its underlying mechanism. Firstly, the …
potential in allergic rhinitis (AR) and to explore its underlying mechanism. Firstly, the …
MicroRNA-19a inhibition directly and indirectly ameliorates Th2 airway inflammation in asthma by targeting RUNX3
S He, J Zhou, Y Ma, W Wang, J Yang - Inflammation, 2023 - Springer
Disruption of T-cell differentiation is characteristic of airway inflammation in allergic asthma.
How miR-19a works in asthma has not been completely elucidated. This study aimed to …
How miR-19a works in asthma has not been completely elucidated. This study aimed to …
Inhibition of house dust mite–induced allergic airways disease by antagonism of microRNA-145 is comparable to glucocorticoid treatment
Background Glucocorticoids are used as mainstay therapy for asthma, but some patients
remain resistant to therapy. MicroRNAs (miRNAs) are important regulators of the immune …
remain resistant to therapy. MicroRNAs (miRNAs) are important regulators of the immune …
Antagonism of mmu-mir-106a attenuates asthma features in allergic murine model
MicroRNAs (miRs) regulate immunological pathways in health and disease, and a number
of miRs have been shown to be altered in mouse models of asthma. The secretion of …
of miRs have been shown to be altered in mouse models of asthma. The secretion of …
[HTML][HTML] MiR-1165-3p suppresses Th2 differentiation via targeting IL-13 and PPM1A in a mouse model of allergic airway inflammation
Z Wang, N Ji, Z Chen, Z Sun, C Wu, W Yu… - Allergy, Asthma & …, 2020 - ncbi.nlm.nih.gov
Purpose CD4+ T cells are essential in the pathogenesis of allergic asthma. We have
previously demonstrated that microRNA-1165-3p (miR-1165-3p) was significantly reduced …
previously demonstrated that microRNA-1165-3p (miR-1165-3p) was significantly reduced …
Mir-20b-induced increase in myeloid-derived suppressor cells in the lungs of mice with chronic asthma
H Ma, H Wang, Y Luo, S Guo… - Annals of Clinical & …, 2017 - Assoc Clin Scientists
Bronchial asthma is a common chronic airway inflammatory disease. MicroRNAs (miRNAs)
play an important role in the pathogenesis of asthma. We have previously shown that miR …
play an important role in the pathogenesis of asthma. We have previously shown that miR …