miR-146a mimics attenuate allergic airway inflammation by impacted group 2 innate lymphoid cells in an ovalbumin-induced asthma mouse model

S Han, C Ma, L Bao, L Lv, M Huang - International Archives of Allergy …, 2018 - karger.com
Background: The prevalence of allergic asthma has increased dramatically. Previous
studies have found that the microRNA 146a (miR-146a) expression in asthma inhibits cell …

[HTML][HTML] Intranasal instillation of miR‑410 targeting IL‑4/IL‑13 attenuates airway inflammation in OVA‑induced asthmatic mice

R Jin, S Hu, X Liu, R Guan, L Lu… - Molecular Medicine …, 2019 - spandidos-publications.com
Asthma is a common chronic inflammatory respiratory disease characterised by airway
inflammation and hyperresponsiveness. The present study was designed to clarify the effect …

The miR‐124‐3p regulates the allergic airway inflammation and remodeling in an ovalbumin‐asthmatic mouse model by inhibiting S100A4

M Liu, S Liu, F Li, C Li, S Chen, X Gao… - Immunity, Inflammation …, 2023 - Wiley Online Library
Objective Asthma is a chronic respiratory disease with an increasing incidence every year.
microRNAs (miRNAs) have been demonstrated to have implications for asthma. However …

MicroRNA-21 is up-regulated in allergic airway inflammation and regulates IL-12p35 expression

TX Lu, A Munitz, ME Rothenberg - The Journal of Immunology, 2009 - journals.aai.org
Allergic airway inflammation is characterized by marked in situ changes in gene and protein
expression, yet the role of microRNAs (miRNAs), a new family of key mRNA regulatory …

MicroRNA-200b deficiency is not sufficient to increase susceptibility to allergen-induced airway inflammation and dysfunction in mice

S Kahnamoui, S Basu, Y Lei, D Patel… - … of Physiology-Lung …, 2023 - journals.physiology.org
MicroRNA-200b (miR-200b) has emerged as a therapeutic option for reducing inflammation
and airway dysfunction in asthma. miR-200b belongs to a family of miRNAs that regulate …

microRNA‐22‐3p plays a protective role in a murine asthma model through the inhibition of the NLRP3–caspase‐1–IL‐1β axis

S Guo, R Chen, L Zhang, M Wu, Y Wei… - Experimental …, 2021 - Wiley Online Library
New Findings What is the central question of this study? How does miR‐22‐3p exert a
protective role in asthma? What is the main finding and its importance? Upregulation of miR …

[HTML][HTML] Effects of microRNA-19b on airway remodeling, airway inflammation and degree of oxidative stress by targeting TSLP through the Stat3 signaling pathway in …

L Ye, Y Mou, J Wang, ML Jin - Oncotarget, 2017 - ncbi.nlm.nih.gov
This study explored the effects of microRNA-19b (miR-19b) on airway remodeling, airway
inflammation, and degree of oxidative stress in a mouse model of asthma. Bioinformatics …

MicroRNA-155 is a critical regulator of type 2 innate lymphoid cells and IL-33 signaling in experimental models of allergic airway inflammation

K Johansson, C Malmhäll, P Ramos-Ramírez… - Journal of Allergy and …, 2017 - Elsevier
Background Allergic airway inflammation is triggered by allergen exposure through several
steps including release of IL-33, which promotes cytokine (IL-5, IL-13) production by type 2 …

miR-410 regulates helper T cell differentiation in ovalbumin-induced asthma through the PI3K-AKT-VEGF signaling pathway

N Tong, D Liu, L Lu, R Lin, R Jin - International Archives of Allergy and …, 2024 - karger.com
Introduction: Asthma has been attributed to Th1/Th2 imbalance and inappropriate Th2
responses to environmental allergens. MicroRNAs (miRNAs), 21 to 23 RNA molecules, are …

MicroRNA-182-5p attenuates asthmatic airway inflammation by targeting NOX4

Z Wang, Y Song, J Jiang, Y Piao, L Li, Q Bai… - Frontiers in …, 2022 - frontiersin.org
Bronchial asthma is characterized by chronic airway inflammation, airway
hyperresponsiveness, and airway remodeling. MicroRNA (miRNA) has recently been …