Are anticholinergic medications associated with increased risk of dementia and behavioral and psychological symptoms of dementia? A nationwide 15-year follow-up …

YP Liu, WC Chien, CH Chung, HA Chang… - Frontiers in …, 2020 - frontiersin.org
Background/Objective In previous reports, the usage of anticholinergic medications has
been associated with an increased risk of dementia with prolonged usage or with a high …

Anticholinergic drugs and the risk of dementia: a systematic review and meta-analysis

YB Zheng, L Shi, XM Zhu, YP Bao, LJ Bai, JQ Li… - Neuroscience & …, 2021 - Elsevier
Dementia is one of the greatest global challenges for public health; however, the
relationship between anticholinergic drugs and dementia remains unclear. The aim of the …

Anticholinergic drugs and incident dementia, mild cognitive impairment and cognitive decline: a meta-analysis

NT Pieper, CM Grossi, WY Chan, YK Loke… - Age and …, 2020 - academic.oup.com
Background the long-term effect of the use of drugs with anticholinergic activity on cognitive
function remains unclear. Methods we conducted a systematic review and meta-analysis of …

Association of Anticholinergic use with incidence of Alzheimer's disease: population-based cohort study

K Joung, S Kim, YH Cho, S Cho - Scientific reports, 2019 - nature.com
Drugs with strong anticholinergic properties are used under a variety of conditions; however,
they can cause various adverse effects including a negative impact on cognitive functions …

Prevalence and determinants of anticholinergic medication use in elderly dementia patients

SD Sura, RM Carnahan, H Chen, RR Aparasu - Drugs & aging, 2013 - Springer
Background People with dementia are sensitive to cognitive side effects of anticholinergic
drugs. However, little is known about the prevalence of anticholinergic medications and its …

Anticholinergic burden and risk of stroke and death in people with different types of dementia

ECK Tan, M Eriksdotter… - Journal of …, 2018 - content.iospress.com
Background: Anticholinergic burden is associated with poorer cognitive and functional
outcomes in people with dementia. However, the impact of anticholinergics on significant …

Association between using medications with anticholinergic properties and short‐term cognitive decline among older men: A retrospective cohort study in Taiwan

YH Wu, CJ Wang, CH Hung, LY Chen… - Geriatrics & …, 2017 - Wiley Online Library
Aim The use of anticholinergic drugs had been strongly linked to adverse health outcomes
among older adults, especially in cognitive impairment or dementia. The present study …

Anticholinergic drug exposure and the risk of dementia: a nested case-control study

CAC Coupland, T Hill, T Dening, R Morriss… - JAMA internal …, 2019 - jamanetwork.com
Importance Anticholinergic medicines have short-term cognitive adverse effects, but it is
uncertain whether long-term use of these drugs is associated with an increased risk of …

Association between anticholinergic medication use and risk of dementia among patients with Parkinson's disease

JJ Sheu, MT Tsai, SR Erickson… - … : The Journal of Human …, 2019 - Wiley Online Library
Study Objectives To evaluate the association between anticholinergic medication use,
categorized by anticholinergic cognitive burden (primary objective) and cumulative dose …

Association between anticholinergic burden and dementia in UK Biobank

J Mur, TC Russ, SR Cox, RE Marioni… - … Research & Clinical …, 2022 - Wiley Online Library
Background Previous studies on the relationship between anticholinergic drugs and
dementia have reported heterogeneous results. This variability could be due to different …