Proteomics uncovers extreme heterogeneity in the Staphylococcus aureus exoproteome due to genomic plasticity and variant gene regulation
AK Ziebandt, H Kusch, M Degner, S Jaglitz… - …, 2010 - Wiley Online Library
Sequencing of at least 13 Staphylococcus aureus isolates has shown that genomic plasticity
impacts significantly on the repertoire of virulence factors. However, genome sequencing …
impacts significantly on the repertoire of virulence factors. However, genome sequencing …
Proteomic approaches to study Staphylococcus aureus pathogenesis
P François, A Scherl, D Hochstrasser, J Schrenzel - Journal of proteomics, 2010 - Elsevier
Staphylococcus aureus is an important human and veterinary pathogen that causes a wide
variety of infections ranging from benign skin infections to life threatening diseases …
variety of infections ranging from benign skin infections to life threatening diseases …
A proteomic view of cell physiology and virulence of Staphylococcus aureus
M Hecker, D Becher, S Fuchs, S Engelmann - International Journal of …, 2010 - Elsevier
Staphylococcus aureus is a human pathogen that has advanced to a main problem in
hospital settings since effective treatment options for infections caused by this pathogen are …
hospital settings since effective treatment options for infections caused by this pathogen are …
[HTML][HTML] A Proteomic View of an Important Human Pathogen – Towards the Quantification of the Entire Staphylococcus aureus Proteome
The genome sequence is the “blue-print of life,” but proteomics provides the link to the actual
physiology of living cells. Because of their low complexity bacteria are excellent model …
physiology of living cells. Because of their low complexity bacteria are excellent model …
[HTML][HTML] From genotype to phenotype: can systems biology be used to predict Staphylococcus aureus virulence?
With the advent of high-throughput whole-genome sequencing, it is now possible to
sequence a bacterial genome in a matter of hours. However, although the presence or …
sequence a bacterial genome in a matter of hours. However, although the presence or …
[HTML][HTML] Exploring the transcriptome of Staphylococcus aureus in its natural niche
Staphylococcus aureus is an important human pathogen and commensal, where the human
nose is the predominant reservoir. To better understand its behavior in this environmental …
nose is the predominant reservoir. To better understand its behavior in this environmental …
[HTML][HTML] A global Staphylococcus aureus proteome resource applied to the in vivo characterization of host-pathogen interactions
S Michalik, M Depke, A Murr, M Gesell Salazar… - Scientific Reports, 2017 - nature.com
Data-independent acquisition mass spectrometry promises higher performance in terms of
quantification and reproducibility compared to data-dependent acquisition mass …
quantification and reproducibility compared to data-dependent acquisition mass …
Small colony variants of Staphylococcus aureus reveal distinct protein profiles
A Kriegeskorte, S König, G Sander, A Pirkl… - …, 2011 - Wiley Online Library
Small‐colony variants (SCVs) of Staphylococcus aureus represent a slow‐growing
subpopulation causing chronic and relapsing infections due to their physiological adaptation …
subpopulation causing chronic and relapsing infections due to their physiological adaptation …
Genome-Wide Analysis of Ruminant Staphylococcus aureus Reveals Diversification of the Core Genome
NL Ben Zakour, DE Sturdevant, S Even… - Journal of …, 2008 - Am Soc Microbiol
Staphylococcus aureus causes disease in humans and a wide array of animals. Of note, S.
aureus mastitis of ruminants, including cows, sheep, and goats, results in major economic …
aureus mastitis of ruminants, including cows, sheep, and goats, results in major economic …
[HTML][HTML] Towards the characterization of the hidden world of small proteins in Staphylococcus aureus, a proteogenomics approach
S Fuchs, M Kucklick, E Lehmann, A Beckmann… - PLoS …, 2021 - journals.plos.org
Small proteins play essential roles in bacterial physiology and virulence, however,
automated algorithms for genome annotation are often not yet able to accurately predict the …
automated algorithms for genome annotation are often not yet able to accurately predict the …